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7OVC

Structure of the human UFC1 protein in complex with the UBA5 C-terminal UFC1-binding motif.

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0007420biological_processbrain development
A0032649biological_processregulation of type II interferon production
A0034976biological_processresponse to endoplasmic reticulum stress
A0061657molecular_functionUFM1 conjugating enzyme activity
A0061709biological_processreticulophagy
A0070062cellular_componentextracellular exosome
A0071568molecular_functionUFM1 transferase activity
A0071569biological_processprotein ufmylation
A1990592biological_processprotein K69-linked ufmylation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8VE47
ChainResidueDetails
BSER393

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1) => ECO:0000269|PubMed:35926457
ChainResidueDetails
ALYS122

223532

PDB entries from 2024-08-07

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