7OUE

Crystal structure of a trapped Pab-AGOG/single-standed DNA covalent intermediate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000702	molecular_function	oxidized base lesion DNA N-glycosylase activity
A	0003824	molecular_function	catalytic activity
A	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0016787	molecular_function	hydrolase activity
A	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
A	0016829	molecular_function	lyase activity
A	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C	0000702	molecular_function	oxidized base lesion DNA N-glycosylase activity
C	0003824	molecular_function	catalytic activity
C	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
C	0006281	biological_process	DNA repair
C	0006284	biological_process	base-excision repair
C	0016787	molecular_function	hydrolase activity
C	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
C	0016829	molecular_function	lyase activity
C	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E	0000702	molecular_function	oxidized base lesion DNA N-glycosylase activity
E	0003824	molecular_function	catalytic activity
E	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
E	0006281	biological_process	DNA repair
E	0006284	biological_process	base-excision repair
E	0016787	molecular_function	hydrolase activity
E	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
E	0016829	molecular_function	lyase activity
E	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G	0000702	molecular_function	oxidized base lesion DNA N-glycosylase activity
G	0003824	molecular_function	catalytic activity
G	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
G	0006281	biological_process	DNA repair
G	0006284	biological_process	base-excision repair
G	0016787	molecular_function	hydrolase activity
G	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
G	0016829	molecular_function	lyase activity
G	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Schiff-base intermediate with DNA => ECO:0000255|HAMAP-Rule:MF_01168

Chain	Residue	Details
A	LYS142
C	LYS142
E	LYS142
G	LYS142

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01168

Chain	Residue	Details
A	ASP174
C	ASP174
E	ASP174
G	ASP174

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site_id	SWS_FT_FI3
Number of Residues	28
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01168

Chain	Residue	Details
A	GLN24
E	TRP212
G	GLN24
G	SER51
G	TRP62
G	PHE146
G	PRO172
G	ASP208
G	TRP212
A	SER51
A	TRP62
A	PHE146
A	PRO172
A	ASP208
A	TRP212
C	GLN24
C	SER51
C	TRP62
C	PHE146
C	PRO172
C	ASP208
C	TRP212
E	GLN24
E	SER51
E	TRP62
E	PHE146
E	PRO172
E	ASP208

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