7OKJ

Crystal structure of human BCL6 BTB domain in complex with compound 12c and its enantiomer 12b

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue VHN A 201

Chain	Residue
A	ASN21
A	GLN113
A	GLU115
A	VHZ202
A	HOH310
A	HOH317
A	HOH349
A	HOH388
A	HOH404
A	HOH423
A	HOH442
A	ARG24
A	LEU25
A	ARG28
A	MET51
A	ALA52
A	CYS53
A	GLY55
A	TYR58

---

site_id	AC2
Number of Residues	22
Details	binding site for residue VHZ A 202

Chain	Residue
A	ASP17
A	ASN21
A	ARG24
A	LEU25
A	ARG28
A	MET51
A	ALA52
A	CYS53
A	GLY55
A	TYR58
A	GLN113
A	MET114
A	GLU115
A	HIS116
A	VHN201
A	HOH325
A	HOH346
A	HOH349
A	HOH398
A	HOH404
A	HOH434
A	HOH474

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO A 203

Chain	Residue
A	ASP63
A	GLN64
A	ARG98
A	GLU99

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO A 204

Chain	Residue
A	ARG28
A	ASP29
A	HOH319
A	HOH344
A	HOH357

---

site_id	AC5
Number of Residues	2
Details	binding site for residue EDO A 205

Chain	Residue
A	TYR111
B	ALA5

---

site_id	AC6
Number of Residues	4
Details	binding site for residue EDO A 206

Chain	Residue
A	GLU99
A	ILE125
A	SER128
A	HOH302

---

site_id	AC7
Number of Residues	2
Details	binding site for residue EDO A 207

Chain	Residue
A	GLN42
A	HOH335

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CL A 208

Chain	Residue
A	HIS116
A	VAL117
A	HOH349

---

site_id	AC9
Number of Residues	1
Details	binding site for residue CL A 209

Chain	Residue
A	SER70

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO B 101

Chain	Residue
A	ILE72
A	ASN73
B	TRP1
B	VAL2
B	HOH201

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