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7OIS

mPI3Kd in complex with compound 7

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
AAA0016301molecular_functionkinase activity
AAA0016303molecular_function1-phosphatidylinositol-3-kinase activity
AAA0043491biological_processphosphatidylinositol 3-kinase/protein kinase B signal transduction
AAA0046854biological_processphosphatidylinositol phosphate biosynthetic process
Functional Information from PROSITE/UniProt
site_idPS00915
Number of Residues15
DetailsPI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. FKng.DDLRQDmltlQ
ChainResidueDetails
AAAPHE778-GLN792

site_idPS00916
Number of Residues21
DetailsPI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. ScAgycVatYVLgIgDRHsdN
ChainResidueDetails
AAASER878-ASN898

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:O00329
ChainResidueDetails
AAATYR524

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine; by autocatalysis => ECO:0000250|UniProtKB:O00329
ChainResidueDetails
AAASER1039

227111

PDB entries from 2024-11-06

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