7OE8
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N5-((1R,5S,6r)-3-oxabicyclo[3.1.0]hexan-6-yl)-3-(1H-indol-4-yl)-N7-methyl-2,3-dihydrobenzofuran-5,7-dicarboxamide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | TYR368 |
| A | LYS402 |
| A | ASP407 |
| A | GLU413 |
| A | MET438 |
| A | LYS441 |
| A | HOH603 |
| A | HOH620 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | LYS427 |
| A | ASN429 |
| A | HOH609 |
| A | TYR426 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue V9Q A 503 |
| Chain | Residue |
| A | LYS351 |
| A | TRP370 |
| A | PRO371 |
| A | LEU383 |
| A | TYR428 |
| A | ASN429 |
| A | PRO430 |
| A | VAL435 |
| A | HOH629 |
| A | HOH650 |
| A | HOH651 |
| A | HOH671 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 | |
