7O4D

QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001512	molecular_function	dihydronicotinamide riboside quinone reductase activity
A	0003955	molecular_function	NAD(P)H dehydrogenase (quinone) activity
A	0005515	molecular_function	protein binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0009055	molecular_function	electron transfer activity
A	0016491	molecular_function	oxidoreductase activity
A	0016661	molecular_function	oxidoreductase activity, acting on other nitrogenous compounds as donors
A	0031404	molecular_function	chloride ion binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome
A	0071949	molecular_function	FAD binding
A	1901662	biological_process	quinone catabolic process
A	1904408	molecular_function	melatonin binding
A	1905594	molecular_function	resveratrol binding
B	0001512	molecular_function	dihydronicotinamide riboside quinone reductase activity
B	0003955	molecular_function	NAD(P)H dehydrogenase (quinone) activity
B	0005515	molecular_function	protein binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0009055	molecular_function	electron transfer activity
B	0016491	molecular_function	oxidoreductase activity
B	0016661	molecular_function	oxidoreductase activity, acting on other nitrogenous compounds as donors
B	0031404	molecular_function	chloride ion binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0070062	cellular_component	extracellular exosome
B	0071949	molecular_function	FAD binding
B	1901662	biological_process	quinone catabolic process
B	1904408	molecular_function	melatonin binding
B	1905594	molecular_function	resveratrol binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18254726","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19236722","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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