7O35

Crystal Structure of SARS-CoV-2 N-CTD in complex with GTP (I)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0019013	cellular_component	viral nucleocapsid
B	0003723	molecular_function	RNA binding
B	0019013	cellular_component	viral nucleocapsid
C	0003723	molecular_function	RNA binding
C	0019013	cellular_component	viral nucleocapsid
D	0003723	molecular_function	RNA binding
D	0019013	cellular_component	viral nucleocapsid

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue GTP C 401

Chain	Residue
C	ARG259
D	MET317
D	ALA336
D	ILE337
D	LYS338
D	HOH455
C	ARG262
C	THR282
C	TRP330
C	HOH516
C	HOH518
C	HOH526
C	HOH554
C	HOH598

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	412
Details	Region: {"description":"Dimerization","evidences":[{"source":"HAMAP-Rule","id":"MF_04096","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	320
Details	Region: {"description":"Putative NLRP3 binding","evidences":[{"source":"PubMed","id":"34341353","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"UniProtKB","id":"P59595","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	117
Details	Domain: {"description":"CoV N CTD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01277","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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