7NWU
Co-crystal structure of UPF3B-RRM-NOPS-L with UPF2-MIF4GIII
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| A | 0003676 | molecular_function | nucleic acid binding |
| B | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| B | 0003723 | molecular_function | RNA binding |
| C | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| C | 0003676 | molecular_function | nucleic acid binding |
| D | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| D | 0003723 | molecular_function | RNA binding |
| E | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| E | 0003676 | molecular_function | nucleic acid binding |
| F | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| F | 0003723 | molecular_function | RNA binding |
| G | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| G | 0003676 | molecular_function | nucleic acid binding |
| H | 0000184 | biological_process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| H | 0003723 | molecular_function | RNA binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Region: {"description":"Binds to UPF2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 852 |
| Details | Domain: {"description":"MIF4G 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 80 |
| Details | Region: {"description":"Binds to UPF3B"} |
| Chain | Residue | Details |






