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7NM4

Solution structure of MLKL executioner domain in complex with a fragment

Functional Information from GO Data
ChainGOidnamespacecontents
A0007166biological_processcell surface receptor signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue UJ8 A 201
ChainResidue
ASER-1
AASN3
ALEU4
ALEU42
ALEU45
APRO54
ASER55
ATHR59
AMET62

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues29
DetailsCoiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsSite: {"description":"Target of necrosulfonamide inhibitor","evidences":[{"source":"PubMed","id":"22265413","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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