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7NGF

P2c-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix

Functional Information from GO Data
ChainGOidnamespacecontents
A0004176molecular_functionATP-dependent peptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005524molecular_functionATP binding
A0006508biological_processproteolysis
A0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
A0016887molecular_functionATP hydrolysis activity
A0030163biological_processprotein catabolic process
B0004176molecular_functionATP-dependent peptidase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005524molecular_functionATP binding
B0006508biological_processproteolysis
B0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
B0016887molecular_functionATP hydrolysis activity
B0030163biological_processprotein catabolic process
C0004176molecular_functionATP-dependent peptidase activity
C0004252molecular_functionserine-type endopeptidase activity
C0005524molecular_functionATP binding
C0006508biological_processproteolysis
C0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
C0016887molecular_functionATP hydrolysis activity
C0030163biological_processprotein catabolic process
D0004176molecular_functionATP-dependent peptidase activity
D0004252molecular_functionserine-type endopeptidase activity
D0005524molecular_functionATP binding
D0006508biological_processproteolysis
D0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
D0016887molecular_functionATP hydrolysis activity
D0030163biological_processprotein catabolic process
E0004176molecular_functionATP-dependent peptidase activity
E0004252molecular_functionserine-type endopeptidase activity
E0005524molecular_functionATP binding
E0006508biological_processproteolysis
E0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
E0016887molecular_functionATP hydrolysis activity
E0030163biological_processprotein catabolic process
F0004176molecular_functionATP-dependent peptidase activity
F0004252molecular_functionserine-type endopeptidase activity
F0005524molecular_functionATP binding
F0006508biological_processproteolysis
F0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
F0016887molecular_functionATP hydrolysis activity
F0030163biological_processprotein catabolic process
Functional Information from PROSITE/UniProt
site_idPS01046
Number of Residues9
DetailsLON_SER ATP-dependent serine proteases, lon family, serine active site. DGPSAGCTI
ChainResidueDetails
AASP852-ILE860

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_03120
ChainResidueDetails
ASER855
ELYS898
FSER855
FLYS898
ALYS898
BSER855
BLYS898
CSER855
CLYS898
DSER855
DLYS898
ESER855

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03120
ChainResidueDetails
AGLY523
BGLY523
CGLY523
DGLY523
EGLY523
FGLY523

229183

PDB entries from 2024-12-18

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