7NFV

Structure of SARS-CoV-2 Papain-like protease PLpro

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0006508	biological_process	proteolysis
AAA	0008234	molecular_function	cysteine-type peptidase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	37
Details	ZN_FING: C4-type => ECO:0000255|PROSITE-ProRule:PRU00444

Chain	Residue	Details
AAA	CYS189-CYS226

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444, ECO:0000269|PubMed:32726803

Chain	Residue	Details
AAA	CYS111

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	ACT_SITE: For PL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00444

Chain	Residue	Details
AAA	HIS272
AAA	ASP286

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00444

Chain	Residue	Details
AAA	CYS189
AAA	CYS192
AAA	CYS224
AAA	CYS226

---