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7NDY

Di-phosphorylated Barrier-to-Autointegration Factor (BAF) in complex with LEM domain of Emerin

Functional Information from GO Data
ChainGOidnamespacecontents
A0000785cellular_componentchromatin
A0000793cellular_componentcondensed chromosome
A0003677molecular_functionDNA binding
A0003690molecular_functiondouble-stranded DNA binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005635cellular_componentnuclear envelope
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006325biological_processchromatin organization
A0006979biological_processresponse to oxidative stress
A0007084biological_processmitotic nuclear membrane reassembly
A0009615biological_processresponse to virus
A0010836biological_processnegative regulation of protein ADP-ribosylation
A0015074biological_processDNA integration
A0032480biological_processnegative regulation of type I interferon production
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0045071biological_processnegative regulation of viral genome replication
A0045824biological_processnegative regulation of innate immune response
A0051276biological_processchromosome organization
A0160049biological_processnegative regulation of cGAS/STING signaling pathway
B0000785cellular_componentchromatin
B0000793cellular_componentcondensed chromosome
B0003677molecular_functionDNA binding
B0003690molecular_functiondouble-stranded DNA binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005635cellular_componentnuclear envelope
B0005654cellular_componentnucleoplasm
B0005694cellular_componentchromosome
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006325biological_processchromatin organization
B0006979biological_processresponse to oxidative stress
B0007084biological_processmitotic nuclear membrane reassembly
B0009615biological_processresponse to virus
B0010836biological_processnegative regulation of protein ADP-ribosylation
B0015074biological_processDNA integration
B0032480biological_processnegative regulation of type I interferon production
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0045071biological_processnegative regulation of viral genome replication
B0045824biological_processnegative regulation of innate immune response
B0051276biological_processchromosome organization
B0160049biological_processnegative regulation of cGAS/STING signaling pathway
G0005635cellular_componentnuclear envelope
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
GSER8
GSER171
BTHR2
BTPO3

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
GSER29
BSEP4

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:16972941, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:23186163
ChainResidueDetails
GSER49

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
GSER54

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
GSER60

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163
ChainResidueDetails
GSER87

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
GSER98
GSER173

site_idSWS_FT_FI8
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q63190
ChainResidueDetails
GSER141
GSER142
GSER143

site_idSWS_FT_FI9
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:O08579
ChainResidueDetails
GTYR161

site_idSWS_FT_FI10
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O08579
ChainResidueDetails
GSER175

227344

PDB entries from 2024-11-13

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