7NDG

Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005887	cellular_component	integral component of plasma membrane
B	0007399	biological_process	nervous system development
B	0007411	biological_process	axon guidance
B	0030513	biological_process	positive regulation of BMP signaling pathway
B	0038023	molecular_function	signaling receptor activity
B	0055072	biological_process	iron ion homeostasis
C	0007155	biological_process	cell adhesion
C	0030509	biological_process	BMP signaling pathway
C	0046658	cellular_component	anchored component of plasma membrane
E	0005887	cellular_component	integral component of plasma membrane
E	0007399	biological_process	nervous system development
E	0007411	biological_process	axon guidance
E	0030513	biological_process	positive regulation of BMP signaling pathway
E	0038023	molecular_function	signaling receptor activity
E	0055072	biological_process	iron ion homeostasis
F	0007155	biological_process	cell adhesion
F	0030509	biological_process	BMP signaling pathway
F	0046658	cellular_component	anchored component of plasma membrane
H	0005887	cellular_component	integral component of plasma membrane
H	0007399	biological_process	nervous system development
H	0007411	biological_process	axon guidance
H	0030513	biological_process	positive regulation of BMP signaling pathway
H	0038023	molecular_function	signaling receptor activity
H	0055072	biological_process	iron ion homeostasis
I	0007155	biological_process	cell adhesion
I	0030509	biological_process	BMP signaling pathway
I	0046658	cellular_component	anchored component of plasma membrane
M	0007155	biological_process	cell adhesion
M	0030509	biological_process	BMP signaling pathway
M	0046658	cellular_component	anchored component of plasma membrane
N	0007155	biological_process	cell adhesion
N	0030509	biological_process	BMP signaling pathway
N	0046658	cellular_component	anchored component of plasma membrane
O	0007155	biological_process	cell adhesion
O	0030509	biological_process	BMP signaling pathway
O	0046658	cellular_component	anchored component of plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CdCrhNtaGPeC

Chain	Residue	Details
A	CYS304-CYS315
A	CYS423-CYS434

---

site_id	PS01248
Number of Residues	35
Details	EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cd.CrhntaGpeCdrCkpfhYdrpwqratareane.C

Chain	Residue	Details
A	CYS304-CYS338
A	CYS368-CYS404
A	CYS423-CYS451

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
F	ASN383
D	ASN116
D	ASN131
D	ASN417
C	ASN383
I	ASN383
A	ASN417
G	ASN95
G	ASN116
G	ASN131
G	ASN417
D	ASN95

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
N	ASN120
M	ASN120
O	ASN120

---