7NBU

Structure of the HigB1 toxin mutant K95A from Mycobacterium tuberculosis (Rv1955) and its target, the cspA mRNA, on the E. coli Ribosome.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000027	biological_process	ribosomal large subunit assembly
0	0000049	molecular_function	tRNA binding
0	0002181	biological_process	cytoplasmic translation
0	0003723	molecular_function	RNA binding
0	0003735	molecular_function	structural constituent of ribosome
0	0005737	cellular_component	cytoplasm
0	0005829	cellular_component	cytosol
0	0005840	cellular_component	ribosome
0	0006412	biological_process	translation
0	0022625	cellular_component	cytosolic large ribosomal subunit
0	0046677	biological_process	response to antibiotic
0	1990904	cellular_component	ribonucleoprotein complex
1	0002181	biological_process	cytoplasmic translation
1	0003735	molecular_function	structural constituent of ribosome
1	0005515	molecular_function	protein binding
1	0005737	cellular_component	cytoplasm
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0022625	cellular_component	cytosolic large ribosomal subunit
1	1990904	cellular_component	ribonucleoprotein complex
2	0002181	biological_process	cytoplasmic translation
2	0003735	molecular_function	structural constituent of ribosome
2	0005737	cellular_component	cytoplasm
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0022625	cellular_component	cytosolic large ribosomal subunit
2	1990904	cellular_component	ribonucleoprotein complex
3	0002181	biological_process	cytoplasmic translation
3	0003723	molecular_function	RNA binding
3	0003735	molecular_function	structural constituent of ribosome
3	0005737	cellular_component	cytoplasm
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0019843	molecular_function	rRNA binding
3	0022625	cellular_component	cytosolic large ribosomal subunit
3	1990904	cellular_component	ribonucleoprotein complex
B	0000028	biological_process	ribosomal small subunit assembly
B	0002181	biological_process	cytoplasmic translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0008270	molecular_function	zinc ion binding
B	0015935	cellular_component	small ribosomal subunit
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0006412	biological_process	translation
D	0000028	biological_process	ribosomal small subunit assembly
D	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0006351	biological_process	DNA-templated transcription
D	0006353	biological_process	DNA-templated transcription termination
D	0006412	biological_process	translation
D	0006417	biological_process	regulation of translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0031564	biological_process	transcription antitermination
D	0042254	biological_process	ribosome biogenesis
D	0042274	biological_process	ribosomal small subunit biogenesis
D	0045947	biological_process	negative regulation of translational initiation
D	0046677	biological_process	response to antibiotic
D	0048027	molecular_function	mRNA 5'-UTR binding
D	1990145	biological_process	maintenance of translational fidelity
D	1990904	cellular_component	ribonucleoprotein complex
E	0000028	biological_process	ribosomal small subunit assembly
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
E	0019843	molecular_function	rRNA binding
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0042254	biological_process	ribosome biogenesis
E	0046677	biological_process	response to antibiotic
E	1990145	biological_process	maintenance of translational fidelity
E	1990904	cellular_component	ribonucleoprotein complex
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0006412	biological_process	translation
G	0015935	cellular_component	small ribosomal subunit
H	0000028	biological_process	ribosomal small subunit assembly
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0006417	biological_process	regulation of translation
H	0019843	molecular_function	rRNA binding
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0043488	biological_process	regulation of mRNA stability
H	1990904	cellular_component	ribonucleoprotein complex
I	0000049	molecular_function	tRNA binding
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0015935	cellular_component	small ribosomal subunit
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	1990904	cellular_component	ribonucleoprotein complex
J	0000049	molecular_function	tRNA binding
J	0001072	molecular_function	transcription antitermination factor activity, RNA binding
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006351	biological_process	DNA-templated transcription
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0031564	biological_process	transcription antitermination
J	0032784	biological_process	regulation of DNA-templated transcription elongation
J	0042254	biological_process	ribosome biogenesis
J	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0070181	molecular_function	small ribosomal subunit rRNA binding
K	1990904	cellular_component	ribonucleoprotein complex
L	0000049	molecular_function	tRNA binding
L	0000372	biological_process	Group I intron splicing
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
L	0019843	molecular_function	rRNA binding
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	0033120	biological_process	positive regulation of RNA splicing
L	0034336	molecular_function	misfolded RNA binding
L	0034337	biological_process	RNA folding
L	0046677	biological_process	response to antibiotic
L	1990145	biological_process	maintenance of translational fidelity
L	1990904	cellular_component	ribonucleoprotein complex
M	0000049	molecular_function	tRNA binding
M	0002181	biological_process	cytoplasmic translation
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015935	cellular_component	small ribosomal subunit
M	0019843	molecular_function	rRNA binding
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0000028	biological_process	ribosomal small subunit assembly
N	0000049	molecular_function	tRNA binding
N	0002181	biological_process	cytoplasmic translation
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015935	cellular_component	small ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0006417	biological_process	regulation of translation
O	0019843	molecular_function	rRNA binding
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0070181	molecular_function	small ribosomal subunit rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0000400	molecular_function	four-way junction DNA binding
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0004518	molecular_function	nuclease activity
P	0004519	molecular_function	endonuclease activity
P	0004520	molecular_function	DNA endonuclease activity
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006259	biological_process	DNA metabolic process
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0016787	molecular_function	hydrolase activity
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000028	biological_process	ribosomal small subunit assembly
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0008270	molecular_function	zinc ion binding
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0046677	biological_process	response to antibiotic
Q	0070181	molecular_function	small ribosomal subunit rRNA binding
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
S	0000049	molecular_function	tRNA binding
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0008073	molecular_function	ornithine decarboxylase inhibitor activity
T	0015935	cellular_component	small ribosomal subunit
T	0019843	molecular_function	rRNA binding
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0070181	molecular_function	small ribosomal subunit rRNA binding
T	1990904	cellular_component	ribonucleoprotein complex
U	0000028	biological_process	ribosomal small subunit assembly
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
Y	0001666	biological_process	response to hypoxia
Y	0004518	molecular_function	nuclease activity
Y	0004519	molecular_function	endonuclease activity
Y	0004521	molecular_function	RNA endonuclease activity
Y	0016787	molecular_function	hydrolase activity
Y	0045926	biological_process	negative regulation of growth
Y	0098754	biological_process	detoxification
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0019843	molecular_function	rRNA binding
c	0000027	biological_process	ribosomal large subunit assembly
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005515	molecular_function	protein binding
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0008270	molecular_function	zinc ion binding
c	0015934	cellular_component	large ribosomal subunit
c	0016740	molecular_function	transferase activity
c	0019843	molecular_function	rRNA binding
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
c	1990904	cellular_component	ribonucleoprotein complex
d	0000027	biological_process	ribosomal large subunit assembly
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005515	molecular_function	protein binding
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0019843	molecular_function	rRNA binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	1990904	cellular_component	ribonucleoprotein complex
e	0001070	molecular_function	RNA-binding transcription regulator activity
e	0002181	biological_process	cytoplasmic translation
e	0003677	molecular_function	DNA binding
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005515	molecular_function	protein binding
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006351	biological_process	DNA-templated transcription
e	0006353	biological_process	DNA-templated transcription termination
e	0006412	biological_process	translation
e	0006417	biological_process	regulation of translation
e	0015934	cellular_component	large ribosomal subunit
e	0017148	biological_process	negative regulation of translation
e	0019843	molecular_function	rRNA binding
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	0030371	molecular_function	translation repressor activity
e	0031555	biological_process	transcriptional attenuation
e	0042255	biological_process	ribosome assembly
e	0045892	biological_process	negative regulation of DNA-templated transcription
e	0046677	biological_process	response to antibiotic
e	0048027	molecular_function	mRNA 5'-UTR binding
e	0060698	molecular_function	endoribonuclease inhibitor activity
e	1990904	cellular_component	ribonucleoprotein complex
e	2000766	biological_process	negative regulation of cytoplasmic translation
f	0000027	biological_process	ribosomal large subunit assembly
f	0000049	molecular_function	tRNA binding
f	0002181	biological_process	cytoplasmic translation
f	0003723	molecular_function	RNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0008097	molecular_function	5S rRNA binding
f	0019843	molecular_function	rRNA binding
f	0022625	cellular_component	cytosolic large ribosomal subunit
f	1990904	cellular_component	ribonucleoprotein complex
g	0000027	biological_process	ribosomal large subunit assembly
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0046677	biological_process	response to antibiotic
g	0070180	molecular_function	large ribosomal subunit rRNA binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0003735	molecular_function	structural constituent of ribosome
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
i	0002181	biological_process	cytoplasmic translation
i	0003729	molecular_function	mRNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0008270	molecular_function	zinc ion binding
i	0017148	biological_process	negative regulation of translation
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0048027	molecular_function	mRNA 5'-UTR binding
i	0070180	molecular_function	large ribosomal subunit rRNA binding
i	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	0015934	cellular_component	large ribosomal subunit
j	0019843	molecular_function	rRNA binding
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0070180	molecular_function	large ribosomal subunit rRNA binding
j	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005515	molecular_function	protein binding
k	0005737	cellular_component	cytoplasm
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0015934	cellular_component	large ribosomal subunit
k	0019843	molecular_function	rRNA binding
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	1990904	cellular_component	ribonucleoprotein complex
l	0002181	biological_process	cytoplasmic translation
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0006413	biological_process	translational initiation
l	0008270	molecular_function	zinc ion binding
l	0019843	molecular_function	rRNA binding
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	0046872	molecular_function	metal ion binding
l	1904689	biological_process	negative regulation of cytoplasmic translational initiation
l	1990904	cellular_component	ribonucleoprotein complex
m	0000027	biological_process	ribosomal large subunit assembly
m	0002181	biological_process	cytoplasmic translation
m	0003735	molecular_function	structural constituent of ribosome
m	0005515	molecular_function	protein binding
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	1990904	cellular_component	ribonucleoprotein complex
n	0002181	biological_process	cytoplasmic translation
n	0003723	molecular_function	RNA binding
n	0003735	molecular_function	structural constituent of ribosome
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	0008097	molecular_function	5S rRNA binding
n	0019843	molecular_function	rRNA binding
n	0022625	cellular_component	cytosolic large ribosomal subunit
n	1990904	cellular_component	ribonucleoprotein complex
o	0000027	biological_process	ribosomal large subunit assembly
o	0002181	biological_process	cytoplasmic translation
o	0003723	molecular_function	RNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0019843	molecular_function	rRNA binding
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0070180	molecular_function	large ribosomal subunit rRNA binding
o	1990904	cellular_component	ribonucleoprotein complex
p	0000027	biological_process	ribosomal large subunit assembly
p	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
p	0002181	biological_process	cytoplasmic translation
p	0003723	molecular_function	RNA binding
p	0003729	molecular_function	mRNA binding
p	0003735	molecular_function	structural constituent of ribosome
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0017148	biological_process	negative regulation of translation
p	0019843	molecular_function	rRNA binding
p	0022625	cellular_component	cytosolic large ribosomal subunit
p	0070180	molecular_function	large ribosomal subunit rRNA binding
p	1990904	cellular_component	ribonucleoprotein complex
q	0002181	biological_process	cytoplasmic translation
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0019843	molecular_function	rRNA binding
q	0022625	cellular_component	cytosolic large ribosomal subunit
q	1990904	cellular_component	ribonucleoprotein complex
r	0002181	biological_process	cytoplasmic translation
r	0003723	molecular_function	RNA binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005515	molecular_function	protein binding
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0015934	cellular_component	large ribosomal subunit
r	0019843	molecular_function	rRNA binding
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	0042255	biological_process	ribosome assembly
r	0042256	biological_process	cytosolic ribosome assembly
r	0046677	biological_process	response to antibiotic
r	0070180	molecular_function	large ribosomal subunit rRNA binding
r	1902626	biological_process	assembly of large subunit precursor of preribosome
r	1990904	cellular_component	ribonucleoprotein complex
s	0000027	biological_process	ribosomal large subunit assembly
s	0002181	biological_process	cytoplasmic translation
s	0003723	molecular_function	RNA binding
s	0003735	molecular_function	structural constituent of ribosome
s	0005515	molecular_function	protein binding
s	0005737	cellular_component	cytoplasm
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0019843	molecular_function	rRNA binding
s	0022625	cellular_component	cytosolic large ribosomal subunit
s	1990904	cellular_component	ribonucleoprotein complex
t	0000027	biological_process	ribosomal large subunit assembly
t	0002181	biological_process	cytoplasmic translation
t	0003723	molecular_function	RNA binding
t	0003735	molecular_function	structural constituent of ribosome
t	0005515	molecular_function	protein binding
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0019843	molecular_function	rRNA binding
t	0022625	cellular_component	cytosolic large ribosomal subunit
t	0070180	molecular_function	large ribosomal subunit rRNA binding
t	1990904	cellular_component	ribonucleoprotein complex
u	0000027	biological_process	ribosomal large subunit assembly
u	0002181	biological_process	cytoplasmic translation
u	0003723	molecular_function	RNA binding
u	0003735	molecular_function	structural constituent of ribosome
u	0005737	cellular_component	cytoplasm
u	0005829	cellular_component	cytosol
u	0005840	cellular_component	ribosome
u	0006412	biological_process	translation
u	0008097	molecular_function	5S rRNA binding
u	0009314	biological_process	response to radiation
u	0017148	biological_process	negative regulation of translation
u	0019843	molecular_function	rRNA binding
u	0022625	cellular_component	cytosolic large ribosomal subunit
u	1990904	cellular_component	ribonucleoprotein complex
v	0000027	biological_process	ribosomal large subunit assembly
v	0000049	molecular_function	tRNA binding
v	0001558	biological_process	regulation of cell growth
v	0002181	biological_process	cytoplasmic translation
v	0003723	molecular_function	RNA binding
v	0003735	molecular_function	structural constituent of ribosome
v	0005515	molecular_function	protein binding
v	0005737	cellular_component	cytoplasm
v	0005840	cellular_component	ribosome
v	0006412	biological_process	translation
v	0019843	molecular_function	rRNA binding
v	0022625	cellular_component	cytosolic large ribosomal subunit
v	0042256	biological_process	cytosolic ribosome assembly
v	0043022	molecular_function	ribosome binding
v	0090070	biological_process	positive regulation of ribosome biogenesis
v	1902626	biological_process	assembly of large subunit precursor of preribosome
v	1990904	cellular_component	ribonucleoprotein complex
w	0000027	biological_process	ribosomal large subunit assembly
w	0002181	biological_process	cytoplasmic translation
w	0003723	molecular_function	RNA binding
w	0003735	molecular_function	structural constituent of ribosome
w	0005515	molecular_function	protein binding
w	0005737	cellular_component	cytoplasm
w	0005829	cellular_component	cytosol
w	0005840	cellular_component	ribosome
w	0006412	biological_process	translation
w	0019843	molecular_function	rRNA binding
w	0022625	cellular_component	cytosolic large ribosomal subunit
w	1990904	cellular_component	ribonucleoprotein complex
x	0000027	biological_process	ribosomal large subunit assembly
x	0002181	biological_process	cytoplasmic translation
x	0003723	molecular_function	RNA binding
x	0003735	molecular_function	structural constituent of ribosome
x	0005737	cellular_component	cytoplasm
x	0005840	cellular_component	ribosome
x	0006412	biological_process	translation
x	0019843	molecular_function	rRNA binding
x	0022625	cellular_component	cytosolic large ribosomal subunit
x	1990904	cellular_component	ribonucleoprotein complex
y	0000027	biological_process	ribosomal large subunit assembly
y	0002181	biological_process	cytoplasmic translation
y	0003735	molecular_function	structural constituent of ribosome
y	0005737	cellular_component	cytoplasm
y	0005840	cellular_component	ribosome
y	0006412	biological_process	translation
y	0015934	cellular_component	large ribosomal subunit
y	0022625	cellular_component	cytosolic large ribosomal subunit
y	1990904	cellular_component	ribonucleoprotein complex
z	0000027	biological_process	ribosomal large subunit assembly
z	0000302	biological_process	response to reactive oxygen species
z	0002181	biological_process	cytoplasmic translation
z	0003735	molecular_function	structural constituent of ribosome
z	0005515	molecular_function	protein binding
z	0005737	cellular_component	cytoplasm
z	0005829	cellular_component	cytosol
z	0005840	cellular_component	ribosome
z	0006412	biological_process	translation
z	0009314	biological_process	response to radiation
z	0015934	cellular_component	large ribosomal subunit
z	0022625	cellular_component	cytosolic large ribosomal subunit
z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkgvrrp.DGsvirFdgNacVL

Chain	Residue	Details
j	ALA60-LEU86

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA

Chain	Residue	Details
G	SER20-ALA46

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR

Chain	Residue	Details
H	GLY100-ARG117

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHD

Chain	Residue	Details
K	ILE97-IAS119

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
L	LYS43-ARG50

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS

Chain	Residue	Details
Q	GLY56-SER68

---

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI

Chain	Residue	Details
R	ILE21-ILE44

---

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG

Chain	Residue	Details
M	PRO10-GLY38

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
S	ASN53-THR77

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LaaISGQkpLiTkARkS

Chain	Residue	Details
f	LEU57-SER73

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL

Chain	Residue	Details
I	GLY69-LEU87

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
J	ALA29-THR44

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY

Chain	Residue	Details
O	LEU39-TYR69

---

site_id	PS00430
Number of Residues	66
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK

Chain	Residue	Details
s	MET1-LYS66

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV

Chain	Residue	Details
r	LYS83-VAL107

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD

Chain	Residue	Details
c	PRO218-ASP229

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR

Chain	Residue	Details
d	PHE101-ARG124

---

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVILaGeVttp..VtVrglrVTkgAraaIeaaG

Chain	Residue	Details
k	LYS109-GLY139

---

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV

Chain	Residue	Details
g	PRO154-VAL162

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
N	ARG63-ARG85

---

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
C	ALA163-GLY197

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV

Chain	Residue	Details
x	GLN39-VAL53

---

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YtTtKNkrtkPekLElkKFD

Chain	Residue	Details
0	TYR21-ASP40

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
E	GLY28-ILE60

---

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRqGKIWIRVFP

Chain	Residue	Details
l	LYS58-PRO69

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV

Chain	Residue	Details
D	LEU94-VAL118

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TLlgLgLrRigHtVeredtpairgMInaVsfMV

Chain	Residue	Details
y	THR23-VAL55

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ

Chain	Residue	Details
M	ARG87-GLN100

---

site_id	PS00651
Number of Residues	28
Details	RIBOSOMAL_L9 Ribosomal protein L9 signature. GslGdqvnVkaGYarNFLvpqgkAvpaT

Chain	Residue	Details
h	GLY13-THR40

---

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA

Chain	Residue	Details
P	VAL2-ALA11

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG

Chain	Residue	Details
i	VAL105-GLY127

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR

Chain	Residue	Details
1	LYS2-ARG21

---

site_id	PS00828
Number of Residues	27
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CrnCkiVkRdgvIrViCsaepKHkQrQ

Chain	Residue	Details
3	CYS11-GLN37

---

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG

Chain	Residue	Details
v	GLY34-GLY48

---

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTVrGAaKRFkktgkggfkhkhanl.RH

Chain	Residue	Details
2	LYS5-HIS31

---

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR

Chain	Residue	Details
p	LYS54-ARG70

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. MrDMLKAGVHFG

Chain	Residue	Details
B	MET6-GLY17

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP

Chain	Residue	Details
B	PRO158-PRO182

---

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGAVR.KAKLYYLR

Chain	Residue	Details
o	VAL86-ARG101

---

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN

Chain	Residue	Details
F	GLY43-ASN52

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV

Chain	Residue	Details
t	ASP8-VAL25

---

site_id	PS01143
Number of Residues	22
Details	RIBOSOMAL_L31 Ribosomal protein L31 signature. DVcskcHPFFTgkqrdvatg....GR

Chain	Residue	Details
l	ASP117-ARG138

---

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvvEpLITlAK

Chain	Residue	Details
m	ILE34-LYS56

---

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT

Chain	Residue	Details
q	VAL72-THR94

---

site_id	PS01181
Number of Residues	13
Details	RIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK

Chain	Residue	Details
U	ASP13-LYS25

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	68
Details	Domain: {"description":"KH type-2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	63
Details	Domain: {"description":"S5 DRBM"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"3-methylthioaspartic acid","evidences":[{"source":"PubMed","id":"8844851","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	133
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	25
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	11
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	9
Details	Compositional bias: {"description":"Low complexity","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"365579","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"331083","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01365","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	10
Details	Compositional bias: {"description":"Gly residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"N-methylmethionine","evidences":[{"source":"PubMed","id":"786730","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34403461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34504068","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O19","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7O1A","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7O1C","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OIZ","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OJ0","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---