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7NAF

State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model

Functional Information from GO Data
ChainGOidnamespacecontents
B0000027biological_processribosomal large subunit assembly
B0002181biological_processcytoplasmic translation
B0003723molecular_functionRNA binding
B0003735molecular_functionstructural constituent of ribosome
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005840cellular_componentribosome
B0006364biological_processrRNA processing
B0006412biological_processtranslation
B0006414biological_processtranslational elongation
B0022625cellular_componentcytosolic large ribosomal subunit
B1990145biological_processmaintenance of translational fidelity
B1990904cellular_componentribonucleoprotein complex
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0005840cellular_componentribosome
R0006412biological_processtranslation
R0022625cellular_componentcytosolic large ribosomal subunit
U0003735molecular_functionstructural constituent of ribosome
U0005840cellular_componentribosome
U0006412biological_processtranslation
V0002181biological_processcytoplasmic translation
V0003735molecular_functionstructural constituent of ribosome
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0005840cellular_componentribosome
V0006412biological_processtranslation
V0022625cellular_componentcytosolic large ribosomal subunit
V0070180molecular_functionlarge ribosomal subunit rRNA binding
V1990904cellular_componentribonucleoprotein complex
d0003735molecular_functionstructural constituent of ribosome
d0005840cellular_componentribosome
d0006412biological_processtranslation
w0001510biological_processRNA methylation
w0008168molecular_functionmethyltransferase activity
w0032259biological_processmethylation
y0000054biological_processribosomal subunit export from nucleus
y0000460biological_processmaturation of 5.8S rRNA
y0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y0000470biological_processmaturation of LSU-rRNA
y0003743molecular_functiontranslation initiation factor activity
y0005515molecular_functionprotein binding
y0005634cellular_componentnucleus
y0005730cellular_componentnucleolus
y0005737cellular_componentcytoplasm
y0005829cellular_componentcytosol
y0006364biological_processrRNA processing
y0006412biological_processtranslation
y0006413biological_processtranslational initiation
y0030687cellular_componentpreribosome, large subunit precursor
y0042254biological_processribosome biogenesis
y0042256biological_processcytosolic ribosome assembly
y0042273biological_processribosomal large subunit biogenesis
y0043022molecular_functionribosome binding
y0043023molecular_functionribosomal large subunit binding
y1902626biological_processassembly of large subunit precursor of preribosome
Functional Information from PROSITE/UniProt
site_idPS00049
Number of Residues27
DetailsRIBOSOMAL_L14 Ribosomal protein L14 signature. AIVVrqakswrrr.DGvflyFedNagVI
ChainResidueDetails
VALA76-ILE102

site_idPS00474
Number of Residues24
DetailsRIBOSOMAL_L3 Ribosomal protein L3 signature. FeqnemiDaiAvTkGHGfeGvthR
ChainResidueDetails
BPHE209-ARG232

site_idPS01144
Number of Residues15
DetailsRIBOSOMAL_L31E Ribosomal protein L31e signature. VRLApeLNqAiWkRG
ChainResidueDetails
dVAL49-GLY63

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
cLYS53
ySER175

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198
ChainResidueDetails
ySER231
wTRP60
wASP78
wASP94
wASP119

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Pros-methylhistidine => ECO:0000269|PubMed:20864530, ECO:0000269|PubMed:24865971, ECO:0000269|PubMed:26826131
ChainResidueDetails
BHIS243

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
BSER297

site_idSWS_FT_FI5
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
BLYS39
BLYS136

227111

PDB entries from 2024-11-06

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