7NAF

State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000027	biological_process	ribosomal large subunit assembly
B	0002181	biological_process	cytoplasmic translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0006364	biological_process	rRNA processing
B	0006412	biological_process	translation
B	0006414	biological_process	translational elongation
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	1990145	biological_process	maintenance of translational fidelity
B	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0022625	cellular_component	cytosolic large ribosomal subunit
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
V	0002181	biological_process	cytoplasmic translation
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0070180	molecular_function	large ribosomal subunit rRNA binding
V	1990904	cellular_component	ribonucleoprotein complex
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
u	0003735	molecular_function	structural constituent of ribosome
w	0001510	biological_process	RNA methylation
w	0008168	molecular_function	methyltransferase activity
w	0032259	biological_process	methylation
y	0000054	biological_process	ribosomal subunit export from nucleus
y	0000460	biological_process	maturation of 5.8S rRNA
y	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y	0000470	biological_process	maturation of LSU-rRNA
y	0003743	molecular_function	translation initiation factor activity
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005730	cellular_component	nucleolus
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0006364	biological_process	rRNA processing
y	0006412	biological_process	translation
y	0006413	biological_process	translational initiation
y	0030687	cellular_component	preribosome, large subunit precursor
y	0042254	biological_process	ribosome biogenesis
y	0042256	biological_process	cytosolic ribosome assembly
y	0042273	biological_process	ribosomal large subunit biogenesis
y	0043022	molecular_function	ribosome binding
y	0043023	molecular_function	ribosomal large subunit binding
y	1902626	biological_process	assembly of large subunit precursor of preribosome

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AIVVrqakswrrr.DGvflyFedNagVI

Chain	Residue	Details
V	ALA76-ILE102

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FeqnemiDaiAvTkGHGfeGvthR

Chain	Residue	Details
B	PHE209-ARG232

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRLApeLNqAiWkRG

Chain	Residue	Details
d	VAL49-GLY63

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	13
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6,N6-dimethyllysine; by RKM1","evidences":[{"source":"PubMed","id":"17327221","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	29
Details	Coiled coil: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03163","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_03163","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03163","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---