Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0006281 | biological_process | DNA repair |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004518 | molecular_function | nuclease activity |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0006281 | biological_process | DNA repair |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004518 | molecular_function | nuclease activity |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0006281 | biological_process | DNA repair |
Functional Information from PROSITE/UniProt
| site_id | PS00728 |
| Number of Residues | 12 |
| Details | AP_NUCLEASE_F1_3 AP endonucleases family 1 signature 3. NyGsRIDFiLvS |
| Chain | Residue | Details |
| A | ASN322-SER333 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR181 | |
| B | TYR181 | |
| C | TYR181 | |
| D | TYR181 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN222 | |
| B | ASN222 | |
| C | ASN222 | |
| D | ASN222 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLN59 | |
| A | ASN222 | |
| A | ASN224 | |
| A | ASP353 | |
| B | GLN59 | |
| B | ASN222 | |
| B | ASN224 | |
| B | ASP353 | |
| C | GLN59 | |
| C | ASN222 | |
| C | ASN224 | |
| C | ASP353 | |
| D | GLN59 | |
| D | ASN222 | |
| D | ASN224 | |
| D | ASP353 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Transition state stabilizer => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN224 | |
| B | ASN224 | |
| C | ASN224 | |
| D | ASN224 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | SITE: Important for catalytic activity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP328 | |
| B | ASP328 | |
| C | ASP328 | |
| D | ASP328 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | SITE: Interaction with DNA substrate => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS354 | |
| B | HIS354 | |
| C | HIS354 | |
| D | HIS354 | |
