7MI5

Asymmetrical PAM-Non PAM prespacer bound Cas4/Cas1/Cas2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0043571	biological_process	maintenance of CRISPR repeat elements
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0051607	biological_process	defense response to virus
A	0099048	biological_process	CRISPR-cas system
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004527	molecular_function	exonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0043571	biological_process	maintenance of CRISPR repeat elements
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0051607	biological_process	defense response to virus
B	0099048	biological_process	CRISPR-cas system
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004527	molecular_function	exonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0043571	biological_process	maintenance of CRISPR repeat elements
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0051607	biological_process	defense response to virus
C	0099048	biological_process	CRISPR-cas system
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004527	molecular_function	exonuclease activity
D	0016787	molecular_function	hydrolase activity
D	0043571	biological_process	maintenance of CRISPR repeat elements
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0051607	biological_process	defense response to virus
D	0099048	biological_process	CRISPR-cas system
E	0003674	molecular_function	molecular_function
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004521	molecular_function	RNA endonuclease activity
E	0008150	biological_process	biological_process
E	0016787	molecular_function	hydrolase activity
E	0043571	biological_process	maintenance of CRISPR repeat elements
E	0046872	molecular_function	metal ion binding
E	0051607	biological_process	defense response to virus
F	0003674	molecular_function	molecular_function
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0004521	molecular_function	RNA endonuclease activity
F	0008150	biological_process	biological_process
F	0016787	molecular_function	hydrolase activity
F	0043571	biological_process	maintenance of CRISPR repeat elements
F	0046872	molecular_function	metal ion binding
F	0051607	biological_process	defense response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01471

Chain	Residue	Details
E	ASP10
B	CYS187
B	CYS190
B	CYS196
C	CYS22
C	ASP87
C	ASP100
C	CYS187
C	CYS190
C	CYS196
D	CYS22
F	ASP10
D	ASP87
D	ASP100
D	CYS187
D	CYS190
D	CYS196
A	ASP100
A	CYS187
A	CYS190
A	CYS196
B	CYS22
B	ASP87
B	ASP100

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q02ML7

Chain	Residue	Details
A	GLU380
D	GLU380
D	HIS451
D	GLU466
A	HIS451
A	GLU466
B	GLU380
B	HIS451
B	GLU466
C	GLU380
C	HIS451
C	GLU466

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