7MH0

Human CTPS1 bound to CTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000785	cellular_component	chromatin
A	0002376	biological_process	immune system process
A	0003883	molecular_function	CTP synthase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009410	biological_process	response to xenobiotic stimulus
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0019856	biological_process	pyrimidine nucleobase biosynthetic process
A	0032480	biological_process	negative regulation of type I interferon production
A	0042098	biological_process	T cell proliferation
A	0042100	biological_process	B cell proliferation
A	0042802	molecular_function	identical protein binding
A	0044210	biological_process	'de novo' CTP biosynthetic process
A	0044281	biological_process	small molecule metabolic process
A	0097268	cellular_component	cytoophidium
A	0140861	biological_process	DNA repair-dependent chromatin remodeling
A	0160260	molecular_function	protein asparagine deamidase activity
A	0160264	molecular_function	histone H1N76/N77 asparagine deamidase activity
A	1902340	biological_process	negative regulation of chromosome condensation
B	0000166	molecular_function	nucleotide binding
B	0000785	cellular_component	chromatin
B	0002376	biological_process	immune system process
B	0003883	molecular_function	CTP synthase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009410	biological_process	response to xenobiotic stimulus
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0019856	biological_process	pyrimidine nucleobase biosynthetic process
B	0032480	biological_process	negative regulation of type I interferon production
B	0042098	biological_process	T cell proliferation
B	0042100	biological_process	B cell proliferation
B	0042802	molecular_function	identical protein binding
B	0044210	biological_process	'de novo' CTP biosynthetic process
B	0044281	biological_process	small molecule metabolic process
B	0097268	cellular_component	cytoophidium
B	0140861	biological_process	DNA repair-dependent chromatin remodeling
B	0160260	molecular_function	protein asparagine deamidase activity
B	0160264	molecular_function	histone H1N76/N77 asparagine deamidase activity
B	1902340	biological_process	negative regulation of chromosome condensation
C	0000166	molecular_function	nucleotide binding
C	0000785	cellular_component	chromatin
C	0002376	biological_process	immune system process
C	0003883	molecular_function	CTP synthase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009410	biological_process	response to xenobiotic stimulus
C	0016020	cellular_component	membrane
C	0016874	molecular_function	ligase activity
C	0019856	biological_process	pyrimidine nucleobase biosynthetic process
C	0032480	biological_process	negative regulation of type I interferon production
C	0042098	biological_process	T cell proliferation
C	0042100	biological_process	B cell proliferation
C	0042802	molecular_function	identical protein binding
C	0044210	biological_process	'de novo' CTP biosynthetic process
C	0044281	biological_process	small molecule metabolic process
C	0097268	cellular_component	cytoophidium
C	0140861	biological_process	DNA repair-dependent chromatin remodeling
C	0160260	molecular_function	protein asparagine deamidase activity
C	0160264	molecular_function	histone H1N76/N77 asparagine deamidase activity
C	1902340	biological_process	negative regulation of chromosome condensation
D	0000166	molecular_function	nucleotide binding
D	0000785	cellular_component	chromatin
D	0002376	biological_process	immune system process
D	0003883	molecular_function	CTP synthase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006139	biological_process	nucleobase-containing compound metabolic process
D	0006221	biological_process	pyrimidine nucleotide biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009410	biological_process	response to xenobiotic stimulus
D	0016020	cellular_component	membrane
D	0016874	molecular_function	ligase activity
D	0019856	biological_process	pyrimidine nucleobase biosynthetic process
D	0032480	biological_process	negative regulation of type I interferon production
D	0042098	biological_process	T cell proliferation
D	0042100	biological_process	B cell proliferation
D	0042802	molecular_function	identical protein binding
D	0044210	biological_process	'de novo' CTP biosynthetic process
D	0044281	biological_process	small molecule metabolic process
D	0097268	cellular_component	cytoophidium
D	0140861	biological_process	DNA repair-dependent chromatin remodeling
D	0160260	molecular_function	protein asparagine deamidase activity
D	0160264	molecular_function	histone H1N76/N77 asparagine deamidase activity
D	1902340	biological_process	negative regulation of chromosome condensation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1016
Details	Domain: {"description":"Glutamine amidotransferase type-1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"For GATase activity","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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