7MFO
X-ray structure of the L136 Aminotransferase from Acanthamoeba polyphaga mimivirus in the presence of TDP and PMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0000271 | biological_process | polysaccharide biosynthetic process |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0000271 | biological_process | polysaccharide biosynthetic process |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| E | 0000271 | biological_process | polysaccharide biosynthetic process |
| E | 0008483 | molecular_function | transaminase activity |
| E | 0030170 | molecular_function | pyridoxal phosphate binding |
| F | 0000271 | biological_process | polysaccharide biosynthetic process |
| F | 0008483 | molecular_function | transaminase activity |
| F | 0030170 | molecular_function | pyridoxal phosphate binding |
| G | 0000271 | biological_process | polysaccharide biosynthetic process |
| G | 0008483 | molecular_function | transaminase activity |
| G | 0030170 | molecular_function | pyridoxal phosphate binding |
| H | 0000271 | biological_process | polysaccharide biosynthetic process |
| H | 0008483 | molecular_function | transaminase activity |
| H | 0030170 | molecular_function | pyridoxal phosphate binding |
| I | 0000271 | biological_process | polysaccharide biosynthetic process |
| I | 0008483 | molecular_function | transaminase activity |
| I | 0030170 | molecular_function | pyridoxal phosphate binding |
| J | 0000271 | biological_process | polysaccharide biosynthetic process |
| J | 0008483 | molecular_function | transaminase activity |
| J | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue PMP A 401 |
| Chain | Residue |
| A | GLY64 |
| A | TYR307 |
| A | HOH549 |
| A | HOH574 |
| A | HOH615 |
| A | HOH639 |
| A | HOH707 |
| B | ASN229 |
| A | THR65 |
| A | PHE92 |
| A | SER94 |
| A | ASP156 |
| A | ALA158 |
| A | SER180 |
| A | HIS182 |
| A | LYS185 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 402 |
| Chain | Residue |
| A | LYS5 |
| A | PHE301 |
| A | GLU340 |
| A | ILE341 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | LYS263 |
| A | LYS278 |
| A | LYS279 |
| A | ASN280 |
| A | HOH614 |
| J | ASN140 |
| J | ASP144 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 404 |
| Chain | Residue |
| A | LEU166 |
| A | LYS278 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for residue TYD B 401 |
| Chain | Residue |
| A | TRP8 |
| A | VAL9 |
| A | HIS182 |
| A | HIS183 |
| A | THR184 |
| A | TYR306 |
| A | HOH549 |
| B | ASN30 |
| B | GLN31 |
| B | TYR32 |
| B | THR33 |
| B | ASN34 |
| B | HOH510 |
| B | HOH518 |
| B | HOH524 |
| B | HOH543 |
| B | HOH561 |
| B | HOH564 |
| B | HOH581 |
| B | HOH694 |
| B | HOH698 |
| B | HOH739 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue PMP B 402 |
| Chain | Residue |
| A | ASN229 |
| B | GLY64 |
| B | THR65 |
| B | PHE92 |
| B | SER94 |
| B | ASP156 |
| B | ALA158 |
| B | SER180 |
| B | LYS185 |
| B | TYR307 |
| B | HOH501 |
| B | HOH577 |
| B | HOH582 |
| B | HOH644 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue TYD B 403 |
| Chain | Residue |
| A | ASN30 |
| A | GLN31 |
| A | TYR32 |
| A | THR33 |
| A | ASN34 |
| A | HOH572 |
| B | VAL9 |
| B | HIS182 |
| B | HIS183 |
| B | THR184 |
| B | ARG304 |
| B | TYR306 |
| B | HOH501 |
| B | HOH502 |
| B | HOH667 |
| B | HOH725 |
| B | HOH742 |
| B | HOH748 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | ILE207 |
| B | ASN210 |
| B | LEU213 |
| B | ASN215 |
| B | HOH590 |
| B | HOH607 |
| B | HOH734 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | PHE164 |
| B | LYS279 |
| B | HOH740 |
| site_id | AD1 |
| Number of Residues | 16 |
| Details | binding site for residue PMP C 401 |
| Chain | Residue |
| C | ALA158 |
| C | SER180 |
| C | HIS182 |
| C | LYS185 |
| C | TYR307 |
| C | HOH549 |
| C | HOH554 |
| C | HOH604 |
| D | ASN229 |
| D | HOH505 |
| C | ASN63 |
| C | GLY64 |
| C | THR65 |
| C | PHE92 |
| C | SER94 |
| C | ASP156 |
| site_id | AD2 |
| Number of Residues | 14 |
| Details | binding site for residue TYD C 402 |
| Chain | Residue |
| C | ASN30 |
| C | GLN31 |
| C | TYR32 |
| C | THR33 |
| C | ASN34 |
| C | HOH519 |
| C | HOH707 |
| C | HOH736 |
| D | VAL9 |
| D | HIS182 |
| D | HIS183 |
| D | THR184 |
| D | ARG304 |
| D | TYR306 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 403 |
| Chain | Residue |
| C | ASP109 |
| C | LEU114 |
| C | ASP115 |
| C | LEU116 |
| C | LYS141 |
| site_id | AD4 |
| Number of Residues | 20 |
| Details | binding site for residue TYD D 401 |
| Chain | Residue |
| C | TRP8 |
| C | VAL9 |
| C | HIS182 |
| C | HIS183 |
| C | THR184 |
| C | ARG304 |
| C | TYR306 |
| D | ASN30 |
| D | GLN31 |
| D | TYR32 |
| D | THR33 |
| D | ASN34 |
| D | HOH505 |
| D | HOH507 |
| D | HOH510 |
| D | HOH511 |
| D | HOH518 |
| D | HOH521 |
| D | HOH577 |
| D | HOH666 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for residue PMP D 402 |
| Chain | Residue |
| C | ASN229 |
| D | ASN63 |
| D | GLY64 |
| D | THR65 |
| D | PHE92 |
| D | SER94 |
| D | ASP156 |
| D | ALA158 |
| D | SER180 |
| D | LYS185 |
| D | TYR307 |
| D | HOH559 |
| D | HOH561 |
| site_id | AD6 |
| Number of Residues | 14 |
| Details | binding site for residue PMP E 401 |
| Chain | Residue |
| E | ASN63 |
| E | GLY64 |
| E | THR65 |
| E | PHE92 |
| E | SER94 |
| E | ASP156 |
| E | ALA158 |
| E | SER180 |
| E | LYS185 |
| E | TYR307 |
| E | HOH504 |
| E | HOH541 |
| E | HOH647 |
| F | ASN229 |
| site_id | AD7 |
| Number of Residues | 21 |
| Details | binding site for residue TYD E 402 |
| Chain | Residue |
| E | TRP8 |
| E | VAL9 |
| E | HIS182 |
| E | HIS183 |
| E | THR184 |
| E | ARG304 |
| E | TYR306 |
| E | HOH502 |
| E | HOH504 |
| E | HOH561 |
| E | HOH588 |
| E | HOH596 |
| E | HOH686 |
| E | HOH740 |
| E | HOH748 |
| F | ASN30 |
| F | GLN31 |
| F | TYR32 |
| F | THR33 |
| F | ASN34 |
| F | HOH518 |
| site_id | AD8 |
| Number of Residues | 19 |
| Details | binding site for residue TYD E 403 |
| Chain | Residue |
| E | ASN30 |
| E | GLN31 |
| E | TYR32 |
| E | THR33 |
| E | ASN34 |
| E | HOH501 |
| E | HOH506 |
| E | HOH510 |
| E | HOH516 |
| E | HOH626 |
| E | HOH689 |
| E | HOH742 |
| E | HOH773 |
| F | VAL9 |
| F | HIS182 |
| F | HIS183 |
| F | THR184 |
| F | ARG304 |
| F | TYR306 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 404 |
| Chain | Residue |
| E | HOH515 |
| E | HOH546 |
| E | HOH580 |
| E | HOH623 |
| site_id | AE1 |
| Number of Residues | 15 |
| Details | binding site for residue PMP F 401 |
| Chain | Residue |
| E | ASN229 |
| F | ASN63 |
| F | GLY64 |
| F | THR65 |
| F | PHE92 |
| F | SER94 |
| F | ASP156 |
| F | ALA158 |
| F | SER180 |
| F | LYS185 |
| F | TYR307 |
| F | HOH548 |
| F | HOH581 |
| F | HOH586 |
| F | HOH596 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 402 |
| Chain | Residue |
| F | ASP109 |
| F | LEU114 |
| F | ASP115 |
| F | LEU116 |
| F | LYS141 |
| site_id | AE3 |
| Number of Residues | 14 |
| Details | binding site for residue PMP G 401 |
| Chain | Residue |
| G | ASN63 |
| G | GLY64 |
| G | THR65 |
| G | PHE92 |
| G | SER94 |
| G | ASP156 |
| G | ALA158 |
| G | SER180 |
| G | LYS185 |
| G | TYR307 |
| G | HOH535 |
| G | HOH572 |
| H | ASN229 |
| H | HOH506 |
| site_id | AE4 |
| Number of Residues | 12 |
| Details | binding site for residue TYD G 402 |
| Chain | Residue |
| G | ASN30 |
| G | GLN31 |
| G | TYR32 |
| G | THR33 |
| G | ASN34 |
| G | HOH526 |
| H | VAL9 |
| H | HIS183 |
| H | THR184 |
| H | ARG304 |
| H | TYR306 |
| H | HOH673 |
| site_id | AE5 |
| Number of Residues | 20 |
| Details | binding site for residue TYD H 401 |
| Chain | Residue |
| G | TRP8 |
| G | VAL9 |
| G | HIS182 |
| G | HIS183 |
| G | THR184 |
| G | ARG304 |
| G | TYR306 |
| H | ASN30 |
| H | GLN31 |
| H | TYR32 |
| H | THR33 |
| H | ASN34 |
| H | HOH502 |
| H | HOH503 |
| H | HOH506 |
| H | HOH510 |
| H | HOH514 |
| H | HOH623 |
| H | HOH626 |
| H | HOH638 |
| site_id | AE6 |
| Number of Residues | 13 |
| Details | binding site for residue PMP H 402 |
| Chain | Residue |
| G | ASN229 |
| H | GLY64 |
| H | THR65 |
| H | PHE92 |
| H | SER94 |
| H | ASP156 |
| H | ALA158 |
| H | SER180 |
| H | HIS182 |
| H | LYS185 |
| H | TYR307 |
| H | HOH595 |
| H | HOH604 |
| site_id | AE7 |
| Number of Residues | 14 |
| Details | binding site for residue PMP I 401 |
| Chain | Residue |
| I | ASN63 |
| I | GLY64 |
| I | THR65 |
| I | THR91 |
| I | PHE92 |
| I | SER94 |
| I | ASP156 |
| I | ALA158 |
| I | SER180 |
| I | LYS185 |
| I | TYR307 |
| I | HOH546 |
| I | HOH548 |
| J | ASN229 |
| site_id | AE8 |
| Number of Residues | 17 |
| Details | binding site for residue TYD I 402 |
| Chain | Residue |
| I | ASN30 |
| I | GLN31 |
| I | TYR32 |
| I | THR33 |
| I | ASN34 |
| I | HOH502 |
| I | HOH518 |
| I | HOH553 |
| I | HOH581 |
| I | HOH604 |
| J | TRP8 |
| J | VAL9 |
| J | HIS182 |
| J | HIS183 |
| J | THR184 |
| J | ARG304 |
| J | TYR306 |
| site_id | AE9 |
| Number of Residues | 17 |
| Details | binding site for residue TYD J 401 |
| Chain | Residue |
| I | TRP8 |
| I | HIS183 |
| I | THR184 |
| I | ARG304 |
| I | TYR306 |
| I | HOH627 |
| J | ASN30 |
| J | GLN31 |
| J | TYR32 |
| J | THR33 |
| J | ASN34 |
| J | HOH501 |
| J | HOH506 |
| J | HOH544 |
| J | HOH573 |
| J | HOH655 |
| J | HOH690 |
| site_id | AF1 |
| Number of Residues | 14 |
| Details | binding site for residue PMP J 402 |
| Chain | Residue |
| I | ASN229 |
| J | GLY64 |
| J | THR65 |
| J | PHE92 |
| J | SER94 |
| J | ASP156 |
| J | ALA158 |
| J | SER180 |
| J | HIS182 |
| J | LYS185 |
| J | TYR307 |
| J | HOH518 |
| J | HOH559 |
| J | HOH579 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO J 403 |
| Chain | Residue |
| J | ARG199 |
| J | HOH637 |
| J | HOH646 |
| J | HOH672 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO J 404 |
| Chain | Residue |
| J | ASP109 |
| J | ASP115 |
| J | LEU116 |
| J | LYS141 |
| J | HOH624 |
