7M5U
Crystal structure of human MPP8 chromodomain in complex with peptidomimetic ligand UNC5246
Functional Information from PROSITE/UniProt
| site_id | PS00598 |
| Number of Residues | 21 |
| Details | CHROMO_1 Chromo domain signature. YkVRWkGYtsddd.TWEPeihL |
| Chain | Residue | Details |
| A | TYR76-LEU96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Region: {"description":"Histone H3K9me3 binding","evidences":[{"source":"PubMed","id":"21419134","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with histone H3K9me3","evidences":[{"source":"PubMed","id":"21419134","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q3TYA6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
