7LUY
Crystal Structure of guanylate kinase from Bartonella henselae str. Houston-1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004385 | molecular_function | guanylate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006163 | biological_process | purine nucleotide metabolic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0046037 | biological_process | GMP metabolic process |
| A | 0046710 | biological_process | GDP metabolic process |
| B | 0004385 | molecular_function | guanylate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006163 | biological_process | purine nucleotide metabolic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0046037 | biological_process | GMP metabolic process |
| B | 0046710 | biological_process | GDP metabolic process |
| C | 0004385 | molecular_function | guanylate kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006163 | biological_process | purine nucleotide metabolic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0046037 | biological_process | GMP metabolic process |
| C | 0046710 | biological_process | GDP metabolic process |
| D | 0004385 | molecular_function | guanylate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006163 | biological_process | purine nucleotide metabolic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0046037 | biological_process | GMP metabolic process |
| D | 0046710 | biological_process | GDP metabolic process |
| E | 0004385 | molecular_function | guanylate kinase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006163 | biological_process | purine nucleotide metabolic process |
| E | 0016301 | molecular_function | kinase activity |
| E | 0046037 | biological_process | GMP metabolic process |
| E | 0046710 | biological_process | GDP metabolic process |
| F | 0004385 | molecular_function | guanylate kinase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006163 | biological_process | purine nucleotide metabolic process |
| F | 0016301 | molecular_function | kinase activity |
| F | 0046037 | biological_process | GMP metabolic process |
| F | 0046710 | biological_process | GDP metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLY29 |
| A | ALA30 |
| A | GLY31 |
| A | LYS32 |
| A | SER33 |
| A | HOH424 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HOH430 |
| A | HOH454 |
| A | LYS121 |
| A | HIS172 |
| A | SER175 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | LYS75 |
| A | ARG78 |
| B | ARG78 |
| B | TRP86 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG57 |
| A | HIS90 |
| A | ARG162 |
| A | HOH414 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | LYS121 |
| B | HIS172 |
| B | SER175 |
| B | HOH426 |
| B | HOH438 |
| B | HOH459 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| A | ARG78 |
| A | TRP86 |
| B | ARG78 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | HIS90 |
| B | ASN165 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 301 |
| Chain | Residue |
| C | LYS121 |
| C | GLN171 |
| C | HIS172 |
| C | SER175 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 301 |
| Chain | Residue |
| D | GLY29 |
| D | ALA30 |
| D | GLY31 |
| D | LYS32 |
| D | SER33 |
| D | HOH405 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 302 |
| Chain | Residue |
| D | LYS121 |
| D | HIS172 |
| D | ARG174 |
| D | SER175 |
| D | HOH415 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| C | ASN214 |
| D | TRP173 |
| D | ARG174 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | LYS121 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 E 301 |
| Chain | Residue |
| E | GLY29 |
| E | ALA30 |
| E | GLY31 |
| E | LYS32 |
| E | SER33 |
| E | ARG147 |
| E | ARG151 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 E 302 |
| Chain | Residue |
| C | ARG76 |
| E | TYR117 |
| E | HIS172 |
| E | SER175 |
| E | HOH420 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 303 |
| Chain | Residue |
| E | THR34 |
| E | ARG147 |
| E | ARG150 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 304 |
| Chain | Residue |
| E | ASP154 |
| E | SER155 |
| E | GLN156 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 305 |
| Chain | Residue |
| B | ASN214 |
| E | GLN171 |
| E | TRP173 |
| E | ARG174 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO E 306 |
| Chain | Residue |
| E | THR131 |
| E | ASP177 |
| E | GLU199 |
| E | LYS202 |
| E | HOH408 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 F 301 |
| Chain | Residue |
| D | ARG76 |
| F | TYR117 |
| F | HIS172 |
| F | SER175 |
Functional Information from PROSITE/UniProt
| site_id | PS00856 |
| Number of Residues | 18 |
| Details | GUANYLATE_KINASE_1 Guanylate kinase-like signature. TTRqkRpsEvdGlhYhFI |
| Chain | Residue | Details |
| A | THR52-ILE69 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00328 |
| Chain | Residue | Details |
| A | SER26 | |
| B | SER26 | |
| C | SER26 | |
| D | SER26 | |
| E | SER26 | |
| F | SER26 |
