7LT2

Structure of a dsRNA-sensing cGAS-like receptor from the beetle Tribolium castaneum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003725	molecular_function	double-stranded RNA binding
A	0005524	molecular_function	ATP binding
A	0005525	molecular_function	GTP binding
A	0016779	molecular_function	nucleotidyltransferase activity
A	0045087	biological_process	innate immune response
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
A	0140700	molecular_function	3',2'-cyclic GMP-AMP synthase activity
A	1902615	biological_process	immune response involved in response to exogenous dsRNA

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q8N884

Chain	Residue	Details
A	ASP193
A	SER241
A	GLN245
A	LYS266
A	SER278
A	SER58
A	GLU70
A	ASP72

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:34261127, ECO:0007744|PDB:7LT2

Chain	Residue	Details
A	GLU290
A	ASP293
A	ILE289

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