Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | MET298 |
| A | GLU299 |
| A | ASP300 |
| A | PHE301 |
| A | PHE303 |
| A | HIS306 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | GLU140 |
| A | GLU253 |
| A | TRP289 |
| A | EDO503 |
| A | NAG504 |
| A | LEU87 |
| A | SER88 |
| A | ASN139 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | SER88 |
| A | TRP211 |
| A | TRP289 |
| A | GLU305 |
| A | EDO502 |
| A | NAG504 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue NAG A 504 |
| Chain | Residue |
| A | HIS86 |
| A | SER89 |
| A | GLU140 |
| A | TRP211 |
| A | ALA416 |
| A | VAL417 |
| A | SER418 |
| A | PHE422 |
| A | EDO502 |
| A | EDO503 |
| A | HOH603 |
| A | HOH623 |
| A | HOH663 |
| A | HOH703 |
| D | TRP100 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | ASP264 |
| D | ARG65 |
| D | LYS128 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | ARG271 |
| A | LYS272 |
| A | GLU275 |
| A | ARG276 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 507 |
| Chain | Residue |
| A | HIS403 |
| A | ALA404 |
| A | HOH622 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue NAG B 501 |
| Chain | Residue |
| B | HIS86 |
| B | SER89 |
| B | GLU140 |
| B | TRP211 |
| B | ALA416 |
| B | VAL417 |
| B | SER418 |
| B | PHE422 |
| B | EDO502 |
| B | EDO503 |
| B | HOH606 |
| B | HOH613 |
| C | TRP100 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | SER88 |
| B | TRP211 |
| B | GLU305 |
| B | NAG501 |
| B | EDO503 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | SER88 |
| B | ASN139 |
| B | GLU140 |
| B | GLU253 |
| B | TRP289 |
| B | NAG501 |
| B | EDO502 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | TRP17 |
| B | ASN57 |
| B | GLY60 |
| B | ASP63 |
| B | HOH750 |
| C | LEU18 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| B | PRO20 |
| B | TRP22 |
| B | LYS59 |
| B | HOH612 |
| B | HOH617 |
| D | ASP23 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 506 |
| Chain | Residue |
| B | ASP293 |
| B | LYS318 |
| B | HOH601 |
| B | HOH672 |
| B | HOH706 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | ARG65 |
| C | LYS128 |
| C | HOH645 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| A | HOH606 |
| C | SER33 |
| C | GLU34 |
| C | HIS74 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | HOH657 |
| B | LEU18 |
| C | TRP17 |
| C | TYR48 |
| C | ASN57 |
| C | LYS59 |
| site_id | AD8 |
| Number of Residues | 13 |
| Details | binding site for residue NAG C 504 |
| Chain | Residue |
| B | TRP100 |
| C | HIS86 |
| C | SER89 |
| C | GLU140 |
| C | TRP211 |
| C | ALA416 |
| C | VAL417 |
| C | SER418 |
| C | PHE422 |
| C | EDO505 |
| C | EDO506 |
| C | HOH603 |
| C | HOH616 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | SER88 |
| C | TRP211 |
| C | TRP289 |
| C | GLU305 |
| C | NAG504 |
| C | EDO506 |
| site_id | AE1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 506 |
| Chain | Residue |
| C | LEU87 |
| C | SER88 |
| C | ASN139 |
| C | GLU140 |
| C | GLU253 |
| C | TRP289 |
| C | NAG504 |
| C | EDO505 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 507 |
| Chain | Residue |
| C | ARG271 |
| C | LYS272 |
| C | ARG276 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 508 |
| Chain | Residue |
| C | ASP293 |
| C | SER307 |
| C | ASP312 |
| C | LYS318 |
| C | HOH610 |
| C | HOH623 |
| C | HOH636 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 509 |
| Chain | Residue |
| C | LEU369 |
| C | HIS403 |
| C | ALA404 |
| C | HOH693 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 510 |
| Chain | Residue |
| A | ARG65 |
| A | LYS128 |
| C | HIS11 |
| C | EDO511 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 511 |
| Chain | Residue |
| B | TRP55 |
| C | HIS11 |
| C | GLY12 |
| C | PRO295 |
| C | SER297 |
| C | EDO510 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 501 |
| Chain | Residue |
| D | TRP17 |
| D | PRO44 |
| D | ILE45 |
| D | TYR48 |
| D | LEU49 |
| D | GLY60 |
| D | EDO506 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| D | ARG271 |
| D | GLU275 |
| D | ARG276 |
| site_id | AE9 |
| Number of Residues | 13 |
| Details | binding site for residue NAG D 503 |
| Chain | Residue |
| A | TRP100 |
| D | HIS86 |
| D | SER88 |
| D | SER89 |
| D | GLU140 |
| D | TRP211 |
| D | ALA416 |
| D | VAL417 |
| D | SER418 |
| D | EDO504 |
| D | EDO505 |
| D | HOH616 |
| D | HOH678 |
| site_id | AF1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | SER88 |
| D | TRP211 |
| D | PHE213 |
| D | TRP289 |
| D | PHE304 |
| D | GLU305 |
| D | NAG503 |
| D | EDO505 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| D | LEU87 |
| D | SER88 |
| D | ASN139 |
| D | GLU140 |
| D | GLU253 |
| D | TRP289 |
| D | NAG503 |
| D | EDO504 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 506 |
| Chain | Residue |
| A | LEU18 |
| D | TRP17 |
| D | ASN57 |
| D | LYS59 |
| D | EDO501 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 507 |
| Chain | Residue |
| D | ALA62 |
| D | ASP63 |
| D | ARG66 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 508 |
| Chain | Residue |
| A | TRP55 |
| D | HIS11 |
| D | GLY12 |
| D | PRO295 |
| D | SER297 |
| D | EDO509 |
| D | HOH671 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 509 |
| Chain | Residue |
| B | LYS128 |
| D | HIS11 |
| D | EDO508 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 510 |
| Chain | Residue |
| D | ASP293 |
| D | SER307 |
| D | ASP312 |
| D | LYS318 |
| D | HOH613 |
| D | HOH639 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 511 |
| Chain | Residue |
| D | HIS403 |
| D | ALA404 |
| D | GLU406 |
| D | HOH619 |
