7LQN

Glucosamine-6-phosphate Deaminase from H. influenzae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006043	biological_process	glucosamine catabolic process
A	0006044	biological_process	N-acetylglucosamine metabolic process
A	0006046	biological_process	N-acetylglucosamine catabolic process
A	0016787	molecular_function	hydrolase activity
A	0019262	biological_process	N-acetylneuraminate catabolic process
A	0042802	molecular_function	identical protein binding
B	0003824	molecular_function	catalytic activity
B	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006043	biological_process	glucosamine catabolic process
B	0006044	biological_process	N-acetylglucosamine metabolic process
B	0006046	biological_process	N-acetylglucosamine catabolic process
B	0016787	molecular_function	hydrolase activity
B	0019262	biological_process	N-acetylneuraminate catabolic process
B	0042802	molecular_function	identical protein binding
C	0003824	molecular_function	catalytic activity
C	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0006043	biological_process	glucosamine catabolic process
C	0006044	biological_process	N-acetylglucosamine metabolic process
C	0006046	biological_process	N-acetylglucosamine catabolic process
C	0016787	molecular_function	hydrolase activity
C	0019262	biological_process	N-acetylneuraminate catabolic process
C	0042802	molecular_function	identical protein binding
D	0003824	molecular_function	catalytic activity
D	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0006043	biological_process	glucosamine catabolic process
D	0006044	biological_process	N-acetylglucosamine metabolic process
D	0006046	biological_process	N-acetylglucosamine catabolic process
D	0016787	molecular_function	hydrolase activity
D	0019262	biological_process	N-acetylneuraminate catabolic process
D	0042802	molecular_function	identical protein binding
E	0003824	molecular_function	catalytic activity
E	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005975	biological_process	carbohydrate metabolic process
E	0006043	biological_process	glucosamine catabolic process
E	0006044	biological_process	N-acetylglucosamine metabolic process
E	0006046	biological_process	N-acetylglucosamine catabolic process
E	0016787	molecular_function	hydrolase activity
E	0019262	biological_process	N-acetylneuraminate catabolic process
E	0042802	molecular_function	identical protein binding
F	0003824	molecular_function	catalytic activity
F	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005975	biological_process	carbohydrate metabolic process
F	0006043	biological_process	glucosamine catabolic process
F	0006044	biological_process	N-acetylglucosamine metabolic process
F	0006046	biological_process	N-acetylglucosamine catabolic process
F	0016787	molecular_function	hydrolase activity
F	0019262	biological_process	N-acetylneuraminate catabolic process
F	0042802	molecular_function	identical protein binding
G	0003824	molecular_function	catalytic activity
G	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005975	biological_process	carbohydrate metabolic process
G	0006043	biological_process	glucosamine catabolic process
G	0006044	biological_process	N-acetylglucosamine metabolic process
G	0006046	biological_process	N-acetylglucosamine catabolic process
G	0016787	molecular_function	hydrolase activity
G	0019262	biological_process	N-acetylneuraminate catabolic process
G	0042802	molecular_function	identical protein binding
H	0003824	molecular_function	catalytic activity
H	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005975	biological_process	carbohydrate metabolic process
H	0006043	biological_process	glucosamine catabolic process
H	0006044	biological_process	N-acetylglucosamine metabolic process
H	0006046	biological_process	N-acetylglucosamine catabolic process
H	0016787	molecular_function	hydrolase activity
H	0019262	biological_process	N-acetylneuraminate catabolic process
H	0042802	molecular_function	identical protein binding
I	0003824	molecular_function	catalytic activity
I	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005975	biological_process	carbohydrate metabolic process
I	0006043	biological_process	glucosamine catabolic process
I	0006044	biological_process	N-acetylglucosamine metabolic process
I	0006046	biological_process	N-acetylglucosamine catabolic process
I	0016787	molecular_function	hydrolase activity
I	0019262	biological_process	N-acetylneuraminate catabolic process
I	0042802	molecular_function	identical protein binding
J	0003824	molecular_function	catalytic activity
J	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005975	biological_process	carbohydrate metabolic process
J	0006043	biological_process	glucosamine catabolic process
J	0006044	biological_process	N-acetylglucosamine metabolic process
J	0006046	biological_process	N-acetylglucosamine catabolic process
J	0016787	molecular_function	hydrolase activity
J	0019262	biological_process	N-acetylneuraminate catabolic process
J	0042802	molecular_function	identical protein binding
K	0003824	molecular_function	catalytic activity
K	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005975	biological_process	carbohydrate metabolic process
K	0006043	biological_process	glucosamine catabolic process
K	0006044	biological_process	N-acetylglucosamine metabolic process
K	0006046	biological_process	N-acetylglucosamine catabolic process
K	0016787	molecular_function	hydrolase activity
K	0019262	biological_process	N-acetylneuraminate catabolic process
K	0042802	molecular_function	identical protein binding
L	0003824	molecular_function	catalytic activity
L	0004342	molecular_function	glucosamine-6-phosphate deaminase activity
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005975	biological_process	carbohydrate metabolic process
L	0006043	biological_process	glucosamine catabolic process
L	0006044	biological_process	N-acetylglucosamine metabolic process
L	0006046	biological_process	N-acetylglucosamine catabolic process
L	0016787	molecular_function	hydrolase activity
L	0019262	biological_process	N-acetylneuraminate catabolic process
L	0042802	molecular_function	identical protein binding

Functional Information from PROSITE/UniProt

site_id	PS01161
Number of Residues	19
Details	GLC_GALNAC_ISOMERASE Glucosamine/galactosamine-6-phosphate isomerases signature. IksyGkIhLfMgGVGvDGH

Chain	Residue	Details
A	ILE125-HIS143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"description":"Proton acceptor; for enolization step","evidences":[{"source":"HAMAP-Rule","id":"MF_01241","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Active site: {"description":"For ring-opening step","evidences":[{"source":"HAMAP-Rule","id":"MF_01241","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Active site: {"description":"Proton acceptor; for ring-opening step","evidences":[{"source":"HAMAP-Rule","id":"MF_01241","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	60
Details	Site: {"description":"Part of the allosteric site","evidences":[{"source":"HAMAP-Rule","id":"MF_01241","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---