7L9J
Crystal structure of the second bromodomain (BD2) of human BRD2 bound to Ro3280
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue 79C A 501 |
| Chain | Residue |
| A | PRO371 |
| A | HOH602 |
| A | HOH630 |
| A | PHE372 |
| A | VAL376 |
| A | LEU381 |
| A | LEU383 |
| A | TYR386 |
| A | TYR428 |
| A | ASN429 |
| A | HIS433 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | ARG419 |
| A | ARG419 |
| A | HOH632 |
| A | HOH632 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
