Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7L7S

Human mitochondrial chaperonin mHsp60

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0001530	molecular_function	lipopolysaccharide binding
H	0002039	molecular_function	p53 binding
H	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
H	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
H	0003688	molecular_function	DNA replication origin binding
H	0003697	molecular_function	single-stranded DNA binding
H	0003723	molecular_function	RNA binding
H	0003725	molecular_function	double-stranded RNA binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005615	cellular_component	extracellular space
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005759	cellular_component	mitochondrial matrix
H	0005769	cellular_component	early endosome
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0005905	cellular_component	clathrin-coated pit
H	0006457	biological_process	protein folding
H	0006458	biological_process	'de novo' protein folding
H	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
H	0006986	biological_process	response to unfolded protein
H	0008035	molecular_function	high-density lipoprotein particle binding
H	0008637	biological_process	apoptotic mitochondrial changes
H	0009409	biological_process	response to cold
H	0009986	cellular_component	cell surface
H	0016020	cellular_component	membrane
H	0016853	molecular_function	isomerase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0019899	molecular_function	enzyme binding
H	0030135	cellular_component	coated vesicle
H	0030141	cellular_component	secretory granule
H	0031625	molecular_function	ubiquitin protein ligase binding
H	0032727	biological_process	positive regulation of interferon-alpha production
H	0032729	biological_process	positive regulation of type II interferon production
H	0032733	biological_process	positive regulation of interleukin-10 production
H	0032735	biological_process	positive regulation of interleukin-12 production
H	0032755	biological_process	positive regulation of interleukin-6 production
H	0032991	cellular_component	protein-containing complex
H	0034185	molecular_function	apolipoprotein binding
H	0034186	molecular_function	apolipoprotein A-I binding
H	0034514	biological_process	mitochondrial unfolded protein response
H	0042026	biological_process	protein refolding
H	0042100	biological_process	B cell proliferation
H	0042110	biological_process	T cell activation
H	0042113	biological_process	B cell activation
H	0043032	biological_process	positive regulation of macrophage activation
H	0043065	biological_process	positive regulation of apoptotic process
H	0043066	biological_process	negative regulation of apoptotic process
H	0043231	cellular_component	intracellular membrane-bounded organelle
H	0044406	biological_process	adhesion of symbiont to host
H	0045041	biological_process	protein import into mitochondrial intermembrane space
H	0046696	cellular_component	lipopolysaccharide receptor complex
H	0048291	biological_process	isotype switching to IgG isotypes
H	0050821	biological_process	protein stabilization
H	0050870	biological_process	positive regulation of T cell activation
H	0051082	molecular_function	unfolded protein binding
H	0051087	molecular_function	protein-folding chaperone binding
H	0051131	biological_process	chaperone-mediated protein complex assembly
H	0051604	biological_process	protein maturation
H	0051702	biological_process	biological process involved in interaction with symbiont
H	0070062	cellular_component	extracellular exosome
H	0097225	cellular_component	sperm midpiece
H	0097524	cellular_component	sperm plasma membrane
H	0098761	biological_process	cellular response to interleukin-7
H	0140494	cellular_component	migrasome
H	0140662	molecular_function	ATP-dependent protein folding chaperone
I	0001530	molecular_function	lipopolysaccharide binding
I	0002039	molecular_function	p53 binding
I	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
I	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
I	0003688	molecular_function	DNA replication origin binding
I	0003697	molecular_function	single-stranded DNA binding
I	0003723	molecular_function	RNA binding
I	0003725	molecular_function	double-stranded RNA binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005615	cellular_component	extracellular space
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005759	cellular_component	mitochondrial matrix
I	0005769	cellular_component	early endosome
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0005905	cellular_component	clathrin-coated pit
I	0006457	biological_process	protein folding
I	0006458	biological_process	'de novo' protein folding
I	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
I	0006986	biological_process	response to unfolded protein
I	0008035	molecular_function	high-density lipoprotein particle binding
I	0008637	biological_process	apoptotic mitochondrial changes
I	0009409	biological_process	response to cold
I	0009986	cellular_component	cell surface
I	0016020	cellular_component	membrane
I	0016853	molecular_function	isomerase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0019899	molecular_function	enzyme binding
I	0030135	cellular_component	coated vesicle
I	0030141	cellular_component	secretory granule
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0032727	biological_process	positive regulation of interferon-alpha production
I	0032729	biological_process	positive regulation of type II interferon production
I	0032733	biological_process	positive regulation of interleukin-10 production
I	0032735	biological_process	positive regulation of interleukin-12 production
I	0032755	biological_process	positive regulation of interleukin-6 production
I	0032991	cellular_component	protein-containing complex
I	0034185	molecular_function	apolipoprotein binding
I	0034186	molecular_function	apolipoprotein A-I binding
I	0034514	biological_process	mitochondrial unfolded protein response
I	0042026	biological_process	protein refolding
I	0042100	biological_process	B cell proliferation
I	0042110	biological_process	T cell activation
I	0042113	biological_process	B cell activation
I	0043032	biological_process	positive regulation of macrophage activation
I	0043065	biological_process	positive regulation of apoptotic process
I	0043066	biological_process	negative regulation of apoptotic process
I	0043231	cellular_component	intracellular membrane-bounded organelle
I	0044406	biological_process	adhesion of symbiont to host
I	0045041	biological_process	protein import into mitochondrial intermembrane space
I	0046696	cellular_component	lipopolysaccharide receptor complex
I	0048291	biological_process	isotype switching to IgG isotypes
I	0050821	biological_process	protein stabilization
I	0050870	biological_process	positive regulation of T cell activation
I	0051082	molecular_function	unfolded protein binding
I	0051087	molecular_function	protein-folding chaperone binding
I	0051131	biological_process	chaperone-mediated protein complex assembly
I	0051604	biological_process	protein maturation
I	0051702	biological_process	biological process involved in interaction with symbiont
I	0070062	cellular_component	extracellular exosome
I	0097225	cellular_component	sperm midpiece
I	0097524	cellular_component	sperm plasma membrane
I	0098761	biological_process	cellular response to interleukin-7
I	0140494	cellular_component	migrasome
I	0140662	molecular_function	ATP-dependent protein folding chaperone
J	0001530	molecular_function	lipopolysaccharide binding
J	0002039	molecular_function	p53 binding
J	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
J	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
J	0003688	molecular_function	DNA replication origin binding
J	0003697	molecular_function	single-stranded DNA binding
J	0003723	molecular_function	RNA binding
J	0003725	molecular_function	double-stranded RNA binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005615	cellular_component	extracellular space
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005759	cellular_component	mitochondrial matrix
J	0005769	cellular_component	early endosome
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0005905	cellular_component	clathrin-coated pit
J	0006457	biological_process	protein folding
J	0006458	biological_process	'de novo' protein folding
J	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
J	0006986	biological_process	response to unfolded protein
J	0008035	molecular_function	high-density lipoprotein particle binding
J	0008637	biological_process	apoptotic mitochondrial changes
J	0009409	biological_process	response to cold
J	0009986	cellular_component	cell surface
J	0016020	cellular_component	membrane
J	0016853	molecular_function	isomerase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019899	molecular_function	enzyme binding
J	0030135	cellular_component	coated vesicle
J	0030141	cellular_component	secretory granule
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032727	biological_process	positive regulation of interferon-alpha production
J	0032729	biological_process	positive regulation of type II interferon production
J	0032733	biological_process	positive regulation of interleukin-10 production
J	0032735	biological_process	positive regulation of interleukin-12 production
J	0032755	biological_process	positive regulation of interleukin-6 production
J	0032991	cellular_component	protein-containing complex
J	0034185	molecular_function	apolipoprotein binding
J	0034186	molecular_function	apolipoprotein A-I binding
J	0034514	biological_process	mitochondrial unfolded protein response
J	0042026	biological_process	protein refolding
J	0042100	biological_process	B cell proliferation
J	0042110	biological_process	T cell activation
J	0042113	biological_process	B cell activation
J	0043032	biological_process	positive regulation of macrophage activation
J	0043065	biological_process	positive regulation of apoptotic process
J	0043066	biological_process	negative regulation of apoptotic process
J	0043231	cellular_component	intracellular membrane-bounded organelle
J	0044406	biological_process	adhesion of symbiont to host
J	0045041	biological_process	protein import into mitochondrial intermembrane space
J	0046696	cellular_component	lipopolysaccharide receptor complex
J	0048291	biological_process	isotype switching to IgG isotypes
J	0050821	biological_process	protein stabilization
J	0050870	biological_process	positive regulation of T cell activation
J	0051082	molecular_function	unfolded protein binding
J	0051087	molecular_function	protein-folding chaperone binding
J	0051131	biological_process	chaperone-mediated protein complex assembly
J	0051604	biological_process	protein maturation
J	0051702	biological_process	biological process involved in interaction with symbiont
J	0070062	cellular_component	extracellular exosome
J	0097225	cellular_component	sperm midpiece
J	0097524	cellular_component	sperm plasma membrane
J	0098761	biological_process	cellular response to interleukin-7
J	0140494	cellular_component	migrasome
J	0140662	molecular_function	ATP-dependent protein folding chaperone
K	0001530	molecular_function	lipopolysaccharide binding
K	0002039	molecular_function	p53 binding
K	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
K	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
K	0003688	molecular_function	DNA replication origin binding
K	0003697	molecular_function	single-stranded DNA binding
K	0003723	molecular_function	RNA binding
K	0003725	molecular_function	double-stranded RNA binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005615	cellular_component	extracellular space
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005759	cellular_component	mitochondrial matrix
K	0005769	cellular_component	early endosome
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0005905	cellular_component	clathrin-coated pit
K	0006457	biological_process	protein folding
K	0006458	biological_process	'de novo' protein folding
K	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
K	0006986	biological_process	response to unfolded protein
K	0008035	molecular_function	high-density lipoprotein particle binding
K	0008637	biological_process	apoptotic mitochondrial changes
K	0009409	biological_process	response to cold
K	0009986	cellular_component	cell surface
K	0016020	cellular_component	membrane
K	0016853	molecular_function	isomerase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0019899	molecular_function	enzyme binding
K	0030135	cellular_component	coated vesicle
K	0030141	cellular_component	secretory granule
K	0031625	molecular_function	ubiquitin protein ligase binding
K	0032727	biological_process	positive regulation of interferon-alpha production
K	0032729	biological_process	positive regulation of type II interferon production
K	0032733	biological_process	positive regulation of interleukin-10 production
K	0032735	biological_process	positive regulation of interleukin-12 production
K	0032755	biological_process	positive regulation of interleukin-6 production
K	0032991	cellular_component	protein-containing complex
K	0034185	molecular_function	apolipoprotein binding
K	0034186	molecular_function	apolipoprotein A-I binding
K	0034514	biological_process	mitochondrial unfolded protein response
K	0042026	biological_process	protein refolding
K	0042100	biological_process	B cell proliferation
K	0042110	biological_process	T cell activation
K	0042113	biological_process	B cell activation
K	0043032	biological_process	positive regulation of macrophage activation
K	0043065	biological_process	positive regulation of apoptotic process
K	0043066	biological_process	negative regulation of apoptotic process
K	0043231	cellular_component	intracellular membrane-bounded organelle
K	0044406	biological_process	adhesion of symbiont to host
K	0045041	biological_process	protein import into mitochondrial intermembrane space
K	0046696	cellular_component	lipopolysaccharide receptor complex
K	0048291	biological_process	isotype switching to IgG isotypes
K	0050821	biological_process	protein stabilization
K	0050870	biological_process	positive regulation of T cell activation
K	0051082	molecular_function	unfolded protein binding
K	0051087	molecular_function	protein-folding chaperone binding
K	0051131	biological_process	chaperone-mediated protein complex assembly
K	0051604	biological_process	protein maturation
K	0051702	biological_process	biological process involved in interaction with symbiont
K	0070062	cellular_component	extracellular exosome
K	0097225	cellular_component	sperm midpiece
K	0097524	cellular_component	sperm plasma membrane
K	0098761	biological_process	cellular response to interleukin-7
K	0140494	cellular_component	migrasome
K	0140662	molecular_function	ATP-dependent protein folding chaperone
L	0001530	molecular_function	lipopolysaccharide binding
L	0002039	molecular_function	p53 binding
L	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
L	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
L	0003688	molecular_function	DNA replication origin binding
L	0003697	molecular_function	single-stranded DNA binding
L	0003723	molecular_function	RNA binding
L	0003725	molecular_function	double-stranded RNA binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005615	cellular_component	extracellular space
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005759	cellular_component	mitochondrial matrix
L	0005769	cellular_component	early endosome
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0005905	cellular_component	clathrin-coated pit
L	0006457	biological_process	protein folding
L	0006458	biological_process	'de novo' protein folding
L	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
L	0006986	biological_process	response to unfolded protein
L	0008035	molecular_function	high-density lipoprotein particle binding
L	0008637	biological_process	apoptotic mitochondrial changes
L	0009409	biological_process	response to cold
L	0009986	cellular_component	cell surface
L	0016020	cellular_component	membrane
L	0016853	molecular_function	isomerase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0019899	molecular_function	enzyme binding
L	0030135	cellular_component	coated vesicle
L	0030141	cellular_component	secretory granule
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0032727	biological_process	positive regulation of interferon-alpha production
L	0032729	biological_process	positive regulation of type II interferon production
L	0032733	biological_process	positive regulation of interleukin-10 production
L	0032735	biological_process	positive regulation of interleukin-12 production
L	0032755	biological_process	positive regulation of interleukin-6 production
L	0032991	cellular_component	protein-containing complex
L	0034185	molecular_function	apolipoprotein binding
L	0034186	molecular_function	apolipoprotein A-I binding
L	0034514	biological_process	mitochondrial unfolded protein response
L	0042026	biological_process	protein refolding
L	0042100	biological_process	B cell proliferation
L	0042110	biological_process	T cell activation
L	0042113	biological_process	B cell activation
L	0043032	biological_process	positive regulation of macrophage activation
L	0043065	biological_process	positive regulation of apoptotic process
L	0043066	biological_process	negative regulation of apoptotic process
L	0043231	cellular_component	intracellular membrane-bounded organelle
L	0044406	biological_process	adhesion of symbiont to host
L	0045041	biological_process	protein import into mitochondrial intermembrane space
L	0046696	cellular_component	lipopolysaccharide receptor complex
L	0048291	biological_process	isotype switching to IgG isotypes
L	0050821	biological_process	protein stabilization
L	0050870	biological_process	positive regulation of T cell activation
L	0051082	molecular_function	unfolded protein binding
L	0051087	molecular_function	protein-folding chaperone binding
L	0051131	biological_process	chaperone-mediated protein complex assembly
L	0051604	biological_process	protein maturation
L	0051702	biological_process	biological process involved in interaction with symbiont
L	0070062	cellular_component	extracellular exosome
L	0097225	cellular_component	sperm midpiece
L	0097524	cellular_component	sperm plasma membrane
L	0098761	biological_process	cellular response to interleukin-7
L	0140494	cellular_component	migrasome
L	0140662	molecular_function	ATP-dependent protein folding chaperone
M	0001530	molecular_function	lipopolysaccharide binding
M	0002039	molecular_function	p53 binding
M	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
M	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
M	0003688	molecular_function	DNA replication origin binding
M	0003697	molecular_function	single-stranded DNA binding
M	0003723	molecular_function	RNA binding
M	0003725	molecular_function	double-stranded RNA binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005615	cellular_component	extracellular space
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005759	cellular_component	mitochondrial matrix
M	0005769	cellular_component	early endosome
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0005905	cellular_component	clathrin-coated pit
M	0006457	biological_process	protein folding
M	0006458	biological_process	'de novo' protein folding
M	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
M	0006986	biological_process	response to unfolded protein
M	0008035	molecular_function	high-density lipoprotein particle binding
M	0008637	biological_process	apoptotic mitochondrial changes
M	0009409	biological_process	response to cold
M	0009986	cellular_component	cell surface
M	0016020	cellular_component	membrane
M	0016853	molecular_function	isomerase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0019899	molecular_function	enzyme binding
M	0030135	cellular_component	coated vesicle
M	0030141	cellular_component	secretory granule
M	0031625	molecular_function	ubiquitin protein ligase binding
M	0032727	biological_process	positive regulation of interferon-alpha production
M	0032729	biological_process	positive regulation of type II interferon production
M	0032733	biological_process	positive regulation of interleukin-10 production
M	0032735	biological_process	positive regulation of interleukin-12 production
M	0032755	biological_process	positive regulation of interleukin-6 production
M	0032991	cellular_component	protein-containing complex
M	0034185	molecular_function	apolipoprotein binding
M	0034186	molecular_function	apolipoprotein A-I binding
M	0034514	biological_process	mitochondrial unfolded protein response
M	0042026	biological_process	protein refolding
M	0042100	biological_process	B cell proliferation
M	0042110	biological_process	T cell activation
M	0042113	biological_process	B cell activation
M	0043032	biological_process	positive regulation of macrophage activation
M	0043065	biological_process	positive regulation of apoptotic process
M	0043066	biological_process	negative regulation of apoptotic process
M	0043231	cellular_component	intracellular membrane-bounded organelle
M	0044406	biological_process	adhesion of symbiont to host
M	0045041	biological_process	protein import into mitochondrial intermembrane space
M	0046696	cellular_component	lipopolysaccharide receptor complex
M	0048291	biological_process	isotype switching to IgG isotypes
M	0050821	biological_process	protein stabilization
M	0050870	biological_process	positive regulation of T cell activation
M	0051082	molecular_function	unfolded protein binding
M	0051087	molecular_function	protein-folding chaperone binding
M	0051131	biological_process	chaperone-mediated protein complex assembly
M	0051604	biological_process	protein maturation
M	0051702	biological_process	biological process involved in interaction with symbiont
M	0070062	cellular_component	extracellular exosome
M	0097225	cellular_component	sperm midpiece
M	0097524	cellular_component	sperm plasma membrane
M	0098761	biological_process	cellular response to interleukin-7
M	0140494	cellular_component	migrasome
M	0140662	molecular_function	ATP-dependent protein folding chaperone
N	0001530	molecular_function	lipopolysaccharide binding
N	0002039	molecular_function	p53 binding
N	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
N	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
N	0003688	molecular_function	DNA replication origin binding
N	0003697	molecular_function	single-stranded DNA binding
N	0003723	molecular_function	RNA binding
N	0003725	molecular_function	double-stranded RNA binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005615	cellular_component	extracellular space
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005759	cellular_component	mitochondrial matrix
N	0005769	cellular_component	early endosome
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0005905	cellular_component	clathrin-coated pit
N	0006457	biological_process	protein folding
N	0006458	biological_process	'de novo' protein folding
N	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
N	0006986	biological_process	response to unfolded protein
N	0008035	molecular_function	high-density lipoprotein particle binding
N	0008637	biological_process	apoptotic mitochondrial changes
N	0009409	biological_process	response to cold
N	0009986	cellular_component	cell surface
N	0016020	cellular_component	membrane
N	0016853	molecular_function	isomerase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0019899	molecular_function	enzyme binding
N	0030135	cellular_component	coated vesicle
N	0030141	cellular_component	secretory granule
N	0031625	molecular_function	ubiquitin protein ligase binding
N	0032727	biological_process	positive regulation of interferon-alpha production
N	0032729	biological_process	positive regulation of type II interferon production
N	0032733	biological_process	positive regulation of interleukin-10 production
N	0032735	biological_process	positive regulation of interleukin-12 production
N	0032755	biological_process	positive regulation of interleukin-6 production
N	0032991	cellular_component	protein-containing complex
N	0034185	molecular_function	apolipoprotein binding
N	0034186	molecular_function	apolipoprotein A-I binding
N	0034514	biological_process	mitochondrial unfolded protein response
N	0042026	biological_process	protein refolding
N	0042100	biological_process	B cell proliferation
N	0042110	biological_process	T cell activation
N	0042113	biological_process	B cell activation
N	0043032	biological_process	positive regulation of macrophage activation
N	0043065	biological_process	positive regulation of apoptotic process
N	0043066	biological_process	negative regulation of apoptotic process
N	0043231	cellular_component	intracellular membrane-bounded organelle
N	0044406	biological_process	adhesion of symbiont to host
N	0045041	biological_process	protein import into mitochondrial intermembrane space
N	0046696	cellular_component	lipopolysaccharide receptor complex
N	0048291	biological_process	isotype switching to IgG isotypes
N	0050821	biological_process	protein stabilization
N	0050870	biological_process	positive regulation of T cell activation
N	0051082	molecular_function	unfolded protein binding
N	0051087	molecular_function	protein-folding chaperone binding
N	0051131	biological_process	chaperone-mediated protein complex assembly
N	0051604	biological_process	protein maturation
N	0051702	biological_process	biological process involved in interaction with symbiont
N	0070062	cellular_component	extracellular exosome
N	0097225	cellular_component	sperm midpiece
N	0097524	cellular_component	sperm plasma membrane
N	0098761	biological_process	cellular response to interleukin-7
N	0140494	cellular_component	migrasome
N	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGIVlGGG

Chain	Residue	Details
H	ALA404-GLY415

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269\|PubMed:25918392, ECO:0007744\|PDB:4PJ1

Chain	Residue	Details
H	LYS49
J	ASP85
J	GLY414
J	ASP494
K	LYS49
K	ASP85
K	GLY414
K	ASP494
L	LYS49
L	ASP85
L	GLY414
H	ASP85
L	ASP494
M	LYS49
M	ASP85
M	GLY414
M	ASP494
N	LYS49
N	ASP85
N	GLY414
N	ASP494
H	GLY414
H	ASP494
I	LYS49
I	ASP85
I	GLY414
I	ASP494
J	LYS49

site_id	SWS_FT_FI2
Number of Residues	14
Details	MOD_RES: N6-succinyllysine => ECO:0000250\|UniProtKB:P63038

Chain	Residue	Details
H	LYS5
L	LYS275
M	LYS5
M	LYS275
N	LYS5
N	LYS275
H	LYS275
I	LYS5
I	LYS275
J	LYS5
J	LYS275
K	LYS5
K	LYS275
L	LYS5

site_id	SWS_FT_FI3
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
H	SER41
I	SER41
J	SER41
K	SER41
L	SER41
M	SER41
N	SER41

site_id	SWS_FT_FI4
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
H	SER44
I	SER44
J	SER44
K	SER44
L	SER44
M	SER44
N	SER44

site_id	SWS_FT_FI5
Number of Residues	56
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P63038

Chain	Residue	Details
H	LYS49
I	LYS61
I	LYS65
I	LYS130
I	LYS223
I	LYS266
I	LYS288
I	LYS363
J	LYS49
J	LYS61
J	LYS65
H	LYS61
J	LYS130
J	LYS223
J	LYS266
J	LYS288
J	LYS363
K	LYS49
K	LYS61
K	LYS65
K	LYS130
K	LYS223
H	LYS65
K	LYS266
K	LYS288
K	LYS363
L	LYS49
L	LYS61
L	LYS65
L	LYS130
L	LYS223
L	LYS266
L	LYS288
H	LYS130
L	LYS363
M	LYS49
M	LYS61
M	LYS65
M	LYS130
M	LYS223
M	LYS266
M	LYS288
M	LYS363
N	LYS49
H	LYS223
N	LYS61
N	LYS65
N	LYS130
N	LYS223
N	LYS266
N	LYS288
N	LYS363
H	LYS266
H	LYS288
H	LYS363
I	LYS49

site_id	SWS_FT_FI6
Number of Residues	84
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250\|UniProtKB:P63038

Chain	Residue	Details
H	LYS56
H	LYS326
H	LYS370
H	LYS455
I	LYS56
I	LYS99
I	LYS107
I	LYS165
I	LYS176
I	LYS179
I	LYS192
H	LYS99
I	LYS210
I	LYS224
I	LYS326
I	LYS370
I	LYS455
J	LYS56
J	LYS99
J	LYS107
J	LYS165
J	LYS176
H	LYS107
J	LYS179
J	LYS192
J	LYS210
J	LYS224
J	LYS326
J	LYS370
J	LYS455
K	LYS56
K	LYS99
K	LYS107
H	LYS165
K	LYS165
K	LYS176
K	LYS179
K	LYS192
K	LYS210
K	LYS224
K	LYS326
K	LYS370
K	LYS455
L	LYS56
H	LYS176
L	LYS99
L	LYS107
L	LYS165
L	LYS176
L	LYS179
L	LYS192
L	LYS210
L	LYS224
L	LYS326
L	LYS370
H	LYS179
L	LYS455
M	LYS56
M	LYS99
M	LYS107
M	LYS165
M	LYS176
M	LYS179
M	LYS192
M	LYS210
M	LYS224
H	LYS192
M	LYS326
M	LYS370
M	LYS455
N	LYS56
N	LYS99
N	LYS107
N	LYS165
N	LYS176
N	LYS179
N	LYS192
H	LYS210
N	LYS210
N	LYS224
N	LYS326
N	LYS370
N	LYS455
H	LYS224

site_id	SWS_FT_FI7
Number of Residues	7
Details	MOD_RES: Phosphotyrosine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
H	TYR64
I	TYR64
J	TYR64
K	TYR64
L	TYR64
M	TYR64
N	TYR64

site_id	SWS_FT_FI8
Number of Residues	28
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
H	LYS104
J	LYS243
J	LYS333
J	LYS443
K	LYS104
K	LYS243
K	LYS333
K	LYS443
L	LYS104
L	LYS243
L	LYS333
H	LYS243
L	LYS443
M	LYS104
M	LYS243
M	LYS333
M	LYS443
N	LYS104
N	LYS243
N	LYS333
N	LYS443
H	LYS333
H	LYS443
I	LYS104
I	LYS243
I	LYS333
I	LYS443
J	LYS104

site_id	SWS_FT_FI9
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P63038

Chain	Residue	Details
H	SER384
I	SER384
J	SER384
K	SER384
L	SER384
M	SER384
N	SER384

site_id	SWS_FT_FI10
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
H	SER462
I	SER462
J	SER462
K	SER462
L	SER462
M	SER462
N	SER462

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)