7L6R

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and Manganese (Mn).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004483	molecular_function	mRNA (nucleoside-2'-O-)-methyltransferase activity
B	0003723	molecular_function	RNA binding
B	0008270	molecular_function	zinc ion binding
B	0019079	biological_process	viral genome replication

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01297

Chain	Residue	Details
B	CYS4370
B	CYS4373
B	CYS4381
B	CYS4383
B	CYS4327
B	CYS4330
B	HIS4336
B	CYS4343

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3

Chain	Residue	Details
B	GLN4392

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