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7L4X

YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal

Functional Information from GO Data
ChainGOidnamespacecontents
B0003723molecular_functionRNA binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:31670957, ECO:0007744|PDB:6RT4, ECO:0007744|PDB:6RT5, ECO:0007744|PDB:6RT6, ECO:0007744|PDB:6RT7
ChainResidueDetails
BLYS361
BASP476

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:25242552, ECO:0000269|PubMed:31670957, ECO:0007744|PDB:6RT4, ECO:0007744|PDB:6RT5, ECO:0007744|PDB:6RT6, ECO:0007744|PDB:6RT7
ChainResidueDetails
BTRP377

site_idSWS_FT_FI3
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:25242552
ChainResidueDetails
BTRP428

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER424

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231
ChainResidueDetails
BSER435

226707

PDB entries from 2024-10-30

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