7L3L
Structure of TRAF5 and TRAF6 RING Hetero dimer
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
| B | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| B | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| B | 0016567 | biological_process | protein ubiquitination |
| C | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
| D | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| D | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| D | 0016567 | biological_process | protein ubiquitination |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHrFCkaCI |
| Chain | Residue | Details |
| B | CYS85-ILE94 | |
| A | CYS60-ILE69 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 158 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"17135271","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19825828","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"18093978","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
