7KSL

Substrate-free human mitochondrial LONP1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005524	molecular_function	ATP binding
A	0006508	biological_process	proteolysis
A	0016887	molecular_function	ATP hydrolysis activity
A	0030163	biological_process	protein catabolic process
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005524	molecular_function	ATP binding
B	0006508	biological_process	proteolysis
B	0016887	molecular_function	ATP hydrolysis activity
B	0030163	biological_process	protein catabolic process
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005524	molecular_function	ATP binding
C	0006508	biological_process	proteolysis
C	0016887	molecular_function	ATP hydrolysis activity
C	0030163	biological_process	protein catabolic process
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005524	molecular_function	ATP binding
E	0006508	biological_process	proteolysis
E	0016887	molecular_function	ATP hydrolysis activity
E	0030163	biological_process	protein catabolic process
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005524	molecular_function	ATP binding
F	0006508	biological_process	proteolysis
F	0016887	molecular_function	ATP hydrolysis activity
F	0030163	biological_process	protein catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue ADP C 1000

Chain	Residue
C	TYR492
C	GLY526
C	VAL527
C	GLY528
C	LYS529
C	THR530
C	SER531
C	TYR661

---

site_id	AC2
Number of Residues	15
Details	binding site for residue ADP B 1000

Chain	Residue
B	TYR492
B	GLY526
B	VAL527
B	GLY528
B	LYS529
B	THR530
B	SER531
B	TYR661
B	ILE669
B	TYR673
B	GLN677
B	VAL709
B	ARG710
B	GLN713
B	HIS491

---

site_id	AC3
Number of Residues	11
Details	binding site for residue ADP A 1000

Chain	Residue
A	HIS491
A	TYR492
A	GLY526
A	VAL527
A	GLY528
A	LYS529
A	THR530
A	TYR661
A	ILE669
A	TYR673
A	VAL709

---

site_id	AC4
Number of Residues	11
Details	binding site for residue ADP F 1000

Chain	Residue
F	HIS491
F	TYR492
F	GLY526
F	VAL527
F	GLY528
F	LYS529
F	THR530
F	TYR661
F	ILE669
F	VAL709
F	GLN713

---

site_id	AC5
Number of Residues	10
Details	binding site for residue ADP E 1000

Chain	Residue
E	TYR492
E	GLY526
E	VAL527
E	GLY528
E	LYS529
E	THR530
E	TYR661
E	ILE669
E	VAL709
E	ARG710

---

Functional Information from PROSITE/UniProt

site_id	PS01046
Number of Residues	9
Details	LON_SER ATP-dependent serine proteases, lon family, serine active site. DGPSAGCTI

Chain	Residue	Details
C	ASP852-ILE860

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_03120

Chain	Residue	Details
C	SER855
E	LYS898
C	LYS898
B	SER855
B	LYS898
A	SER855
A	LYS898
F	SER855
F	LYS898
E	SER855

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03120

Chain	Residue	Details
C	GLY523
B	GLY523
A	GLY523
F	GLY523
E	GLY523

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