7KLI
Crystal Structure of Enoyl-[acyl-carrier-protein] reductase [NADH] (InhA) from Mycobacterium abscessus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050343 | molecular_function | trans-2-enoyl-CoA reductase (NADH) activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050343 | molecular_function | trans-2-enoyl-CoA reductase (NADH) activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0050343 | molecular_function | trans-2-enoyl-CoA reductase (NADH) activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0006631 | biological_process | fatty acid metabolic process |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0050343 | molecular_function | trans-2-enoyl-CoA reductase (NADH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | PHE149 |
| A | ASP150 |
| A | ALA190 |
| A | ALA191 |
| A | TRP222 |
| A | PHE259 |
| A | ASP261 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | ARG77 |
| A | HOH425 |
| A | LEU61 |
| A | GLU62 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG9 |
| A | ASN86 |
| A | HOH434 |
| A | HOH466 |
| B | GLU80 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| B | PHE149 |
| B | ASP150 |
| B | ALA190 |
| B | ALA191 |
| B | TRP222 |
| B | ASP261 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | LEU61 |
| B | GLU62 |
| B | ARG77 |
| B | HOH416 |
| B | HOH503 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | ARG9 |
| B | ASN86 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 301 |
| Chain | Residue |
| C | PHE149 |
| C | ASP150 |
| C | ALA190 |
| C | ALA191 |
| C | TRP222 |
| C | PHE259 |
| C | ASP261 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 302 |
| Chain | Residue |
| C | PHE41 |
| C | LEU63 |
| C | ASP64 |
| C | VAL65 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 303 |
| Chain | Residue |
| C | LEU61 |
| C | GLU62 |
| C | ARG77 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| C | SER20 |
| C | ILE21 |
| C | HOH412 |
| C | HOH414 |
| C | HOH475 |
| C | HOH522 |
| C | HOH536 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 301 |
| Chain | Residue |
| D | PHE149 |
| D | ASP150 |
| D | ALA190 |
| D | ALA191 |
| D | TRP222 |
| D | PHE259 |
| D | ASP261 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | LEU63 |
| D | ASP64 |
| D | VAL65 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | LEU61 |
| D | GLU62 |
| D | ARG77 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| D | SER20 |
| D | ILE21 |
| D | HOH401 |
| D | HOH417 |
| D | HOH464 |
