7KKF

Crystal Structure of S. cerevisiae Ess1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0000993	molecular_function	RNA polymerase II complex binding
A	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006369	biological_process	termination of RNA polymerase II transcription
A	0016853	molecular_function	isomerase activity
A	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
A	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
A	2000749	biological_process	positive regulation of rDNA heterochromatin formation
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0000993	molecular_function	RNA polymerase II complex binding
B	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006369	biological_process	termination of RNA polymerase II transcription
B	0016853	molecular_function	isomerase activity
B	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
B	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
B	2000749	biological_process	positive regulation of rDNA heterochromatin formation

Functional Information from PROSITE/UniProt

site_id	PS01096
Number of Residues	21
Details	PPIC_PPIASE_1 PpiC-type peptidyl-prolyl cis-trans isomerase signature. FEaLAkerSdcs.Sykr..GGdLG

Chain	Residue	Details
A	PHE110-GLY130

---

site_id	PS01159
Number of Residues	27
Details	WW_DOMAIN_1 WW/rsp5/WWP domain signature. WtvryskskkreYFfnpetkhSQWEEP

Chain	Residue	Details
A	TRP15-PRO41

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	34
Details	Domain: {"description":"WW","evidences":[{"source":"PROSITE-ProRule","id":"PRU00224","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	226
Details	Domain: {"description":"PpiC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00278","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	23
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	21
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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