7K88

Crystal structure of bovine RPE65 in complex with hexaethylene glycol monooctyl ether

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001523	biological_process	retinoid metabolic process
A	0001786	molecular_function	phosphatidylserine binding
A	0001895	biological_process	retina homeostasis
A	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
A	0004744	molecular_function	obsolete retinal isomerase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0007601	biological_process	visual perception
A	0016020	cellular_component	membrane
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0016787	molecular_function	hydrolase activity
A	0016853	molecular_function	isomerase activity
A	0031210	molecular_function	phosphatidylcholine binding
A	0042572	biological_process	retinol metabolic process
A	0042574	biological_process	retinal metabolic process
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0050251	molecular_function	retinol isomerase activity
A	0050908	biological_process	detection of light stimulus involved in visual perception
A	0052884	molecular_function	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
A	0052885	molecular_function	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
A	1901612	molecular_function	cardiolipin binding
A	1901827	biological_process	zeaxanthin biosynthetic process
B	0001523	biological_process	retinoid metabolic process
B	0001786	molecular_function	phosphatidylserine binding
B	0001895	biological_process	retina homeostasis
B	0003834	molecular_function	beta-carotene 15,15'-dioxygenase activity
B	0004744	molecular_function	obsolete retinal isomerase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005886	cellular_component	plasma membrane
B	0006629	biological_process	lipid metabolic process
B	0007601	biological_process	visual perception
B	0016020	cellular_component	membrane
B	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B	0016787	molecular_function	hydrolase activity
B	0016853	molecular_function	isomerase activity
B	0031210	molecular_function	phosphatidylcholine binding
B	0042572	biological_process	retinol metabolic process
B	0042574	biological_process	retinal metabolic process
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0050251	molecular_function	retinol isomerase activity
B	0050908	biological_process	detection of light stimulus involved in visual perception
B	0052884	molecular_function	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
B	0052885	molecular_function	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
B	1901612	molecular_function	cardiolipin binding
B	1901827	biological_process	zeaxanthin biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19805034","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"15186777","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q16518","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Lipidation: {"description":"S-palmitoyl cysteine; in membrane form","evidences":[{"source":"PubMed","id":"15186777","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---