7JYE

Human Liver Receptor Homolog-1 in Complex with 9ChoP and a Fragment of Tif2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue VQY A 601

Chain	Residue
A	PHE342
A	HIS390
A	ILE416
A	GLY421
A	LEU424
A	GLU465
A	TYR516
A	LYS520
A	HOH707

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	239
Details	Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	11
Details	Region: {"description":"AF-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15897460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22187462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22504882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26416531","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26553876","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ZDU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TX7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DOR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RWV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Motif: {"description":"LXXLL motif 3"}

Chain

Residue

Details

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