7JXS

Crystal Structure Human Immunodeficiency Virus-1 Matrix protein Mutant Q63R Crystal Form 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005198	molecular_function	structural molecule activity
B	0005198	molecular_function	structural molecule activity
C	0005198	molecular_function	structural molecule activity
D	0005198	molecular_function	structural molecule activity
E	0005198	molecular_function	structural molecule activity
F	0005198	molecular_function	structural molecule activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue 12P A 201

Chain	Residue
A	TYR29
B	TRP36
B	ARG39
B	GLU40
B	SER77
B	ASN80
A	LYS32
A	HIS33
A	TRP36
A	GLU40
A	THR81
A	HOH315
B	LYS32
B	HIS33

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 202

Chain	Residue
A	ARG22
A	GLY25
A	LYS26
A	LYS27
A	HOH317

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 203

Chain	Residue
A	VAL35
A	ARG39
B	ARG43
D	ARG43

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 204

Chain	Residue
A	SER72
A	GLU73
A	GLU74
A	HOH306
B	LYS30
B	LYS32

---

site_id	AC5
Number of Residues	6
Details	binding site for residue ACT A 205

Chain	Residue
A	LYS30
A	LYS32
A	HOH303
B	SER72
B	GLU73
B	GLU74

---

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG22
B	GLY25
B	LYS26
B	LYS27

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 B 202

Chain	Residue
A	ARG43
B	ARG39
B	HOH303

---

site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 B 203

Chain	Residue
B	LEU21
B	LYS32
B	HIS33
B	HOH302

---

site_id	AC9
Number of Residues	4
Details	binding site for residue SO4 C 201

Chain	Residue
C	ARG22
C	GLY25
C	LYS26
C	LYS27

---

site_id	AD1
Number of Residues	2
Details	binding site for residue SO4 D 201

Chain	Residue
D	ARG20
F	ARG20

---

site_id	AD2
Number of Residues	6
Details	binding site for residue SO4 D 202

Chain	Residue
D	ARG22
D	GLY25
D	LYS26
D	LYS27
D	HOH305
F	LYS18

---

site_id	AD3
Number of Residues	5
Details	binding site for residue P6G D 203

Chain	Residue
D	LYS32
D	HIS33
D	TRP36
D	THR81
D	HOH304

---

site_id	AD4
Number of Residues	7
Details	binding site for residue SO4 E 201

Chain	Residue
D	LYS26
D	LYS27
E	LYS27
E	LYS30
E	LYS32
E	HOH303
F	LYS18

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 F 201

Chain	Residue
F	ARG22
F	GLY25
F	LYS26
F	LYS27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	144
Details	Region: {"description":"Interaction with Gp41","evidences":[{"source":"PubMed","id":"8918455","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	210
Details	Region: {"description":"Interaction with host CALM1","evidences":[{"source":"UniProtKB","id":"P04591","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	42
Details	Region: {"description":"Interaction with host AP3D1","evidences":[{"source":"PubMed","id":"15766529","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	114
Details	Region: {"description":"Interaction with membrane phosphatidylinositol 4,5-bisphosphate and RNA","evidences":[{"source":"PubMed","id":"16840558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	24
Details	Region: {"description":"Interaction with membrane phosphatidylinositol 4,5-bisphosphate","evidences":[{"source":"PubMed","id":"16840558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	36
Details	Motif: {"description":"Nuclear export signal","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	36
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---