Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008720 | molecular_function | D-lactate dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
| B | 0008720 | molecular_function | D-lactate dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | PHE54 |
| A | THR77 |
| A | TYR101 |
| A | HOH701 |
| B | TRP135 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| B | ARG9 |
| B | GLU11 |
| A | TRP135 |
| A | GLN136 |
| A | LYS137 |
| A | HOH618 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | THR303 |
| A | HOH543 |
| B | GLU143 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| A | TRP135 |
| B | THR77 |
| B | TYR101 |
| B | HOH667 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | LEU117 |
| B | GLU123 |
| B | TYR229 |
| B | ALA254 |
| B | GLY255 |
| B | ARG290 |
| B | HOH549 |
| B | HOH556 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| A | ARG131 |
| A | PHE263 |
| A | HOH568 |
| B | ASN272 |
| B | GLY273 |
| B | ASN275 |
| B | PRO276 |
| B | ILE277 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| A | GLU125 |
| A | VAL128 |
| B | ARG122 |
| B | ILE291 |
| B | ILE292 |
| B | TYR293 |
| B | HOH586 |
| B | HOH594 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 405 |
| Chain | Residue |
| A | GLU143 |
| B | GLU302 |
| B | THR303 |
| B | HOH560 |
Functional Information from PROSITE/UniProt
| site_id | PS00065 |
| Number of Residues | 28 |
| Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGILGtGRIGqaaarlfkgvgaq.VVgFD |
| Chain | Residue | Details |
| A | VAL149-ASP176 | |
| site_id | PS00670 |
| Number of Residues | 23 |
| Details | D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. LLstSDVIsLHmPatkdShhLiN |
| Chain | Residue | Details |
| A | LEU195-ASN217 | |
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKdGvYLVNtARGaVID |
| Chain | Residue | Details |
| A | MET224-ASP240 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"P26297","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P26297","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P30901","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P26297","evidenceCode":"ECO:0000250"}]} |
