7FXO

Crystal Structure of apo human FABP1 monoclinic form III

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0005319	molecular_function	lipid transporter activity
A	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006869	biological_process	lipid transport
A	0008289	molecular_function	lipid binding
A	0015485	molecular_function	cholesterol binding
A	0015908	biological_process	fatty acid transport
A	0015909	biological_process	long-chain fatty acid transport
A	0016209	molecular_function	antioxidant activity
A	0019216	biological_process	regulation of lipid metabolic process
A	0019433	biological_process	triglyceride catabolic process
A	0032934	molecular_function	sterol binding
A	0036042	molecular_function	long-chain fatty acyl-CoA binding
A	0042167	biological_process	heme catabolic process
A	0070062	cellular_component	extracellular exosome
A	0070301	biological_process	cellular response to hydrogen peroxide
A	0071456	biological_process	cellular response to hypoxia
A	0098869	biological_process	cellular oxidant detoxification
A	0120009	biological_process	intermembrane lipid transfer
A	0120013	molecular_function	lipid transfer activity
A	0140104	molecular_function	molecular carrier activity
A	1990748	biological_process	cellular detoxification
B	0003682	molecular_function	chromatin binding
B	0005319	molecular_function	lipid transporter activity
B	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
B	0005504	molecular_function	fatty acid binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005782	cellular_component	peroxisomal matrix
B	0005829	cellular_component	cytosol
B	0006869	biological_process	lipid transport
B	0008289	molecular_function	lipid binding
B	0015485	molecular_function	cholesterol binding
B	0015908	biological_process	fatty acid transport
B	0015909	biological_process	long-chain fatty acid transport
B	0016209	molecular_function	antioxidant activity
B	0019216	biological_process	regulation of lipid metabolic process
B	0019433	biological_process	triglyceride catabolic process
B	0032934	molecular_function	sterol binding
B	0036042	molecular_function	long-chain fatty acyl-CoA binding
B	0042167	biological_process	heme catabolic process
B	0070062	cellular_component	extracellular exosome
B	0070301	biological_process	cellular response to hydrogen peroxide
B	0071456	biological_process	cellular response to hypoxia
B	0098869	biological_process	cellular oxidant detoxification
B	0120009	biological_process	intermembrane lipid transfer
B	0120013	molecular_function	lipid transfer activity
B	0140104	molecular_function	molecular carrier activity
B	1990748	biological_process	cellular detoxification

Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GKYqLqsQeNFEaFMKAI

Chain	Residue	Details
A	GLY5-ILE22

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"3838309","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	14
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P12710","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02692","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P12710","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---