7FJD
Cryo-EM structure of a membrane protein(WT)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0004888 | molecular_function | transmembrane signaling receptor activity |
| a | 0007166 | biological_process | cell surface receptor signaling pathway |
| a | 0016020 | cellular_component | membrane |
| b | 0004888 | molecular_function | transmembrane signaling receptor activity |
| b | 0007166 | biological_process | cell surface receptor signaling pathway |
| b | 0016020 | cellular_component | membrane |
| d | 0004888 | molecular_function | transmembrane signaling receptor activity |
| d | 0007166 | biological_process | cell surface receptor signaling pathway |
| d | 0016020 | cellular_component | membrane |
| e | 0004888 | molecular_function | transmembrane signaling receptor activity |
| e | 0007166 | biological_process | cell surface receptor signaling pathway |
| e | 0016020 | cellular_component | membrane |
| f | 0004888 | molecular_function | transmembrane signaling receptor activity |
| f | 0007166 | biological_process | cell surface receptor signaling pathway |
| f | 0016020 | cellular_component | membrane |
| g | 0004888 | molecular_function | transmembrane signaling receptor activity |
| g | 0007166 | biological_process | cell surface receptor signaling pathway |
| g | 0016020 | cellular_component | membrane |
| m | 0002250 | biological_process | adaptive immune response |
| m | 0002376 | biological_process | immune system process |
| m | 0005886 | cellular_component | plasma membrane |
| m | 0009617 | biological_process | response to bacterium |
| m | 0016020 | cellular_component | membrane |
| m | 0042101 | cellular_component | T cell receptor complex |
| m | 0042105 | cellular_component | alpha-beta T cell receptor complex |
| m | 0046631 | biological_process | alpha-beta T cell activation |
| m | 0050852 | biological_process | T cell receptor signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 91 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 152 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 57 |
| Details | Domain: {"description":"Ig-like"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"8636209","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27791034","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 197 |
| Details | Domain: {"description":"Ig-like C1-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | Region: {"description":"Connecting peptide","evidences":[{"source":"PubMed","id":"27791034","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 92 |
| Details | Region: {"description":"T cell receptor beta variable 19","evidences":[{"source":"PubMed","id":"1833769","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Region: {"description":"CDR1","evidences":[{"source":"PubMed","id":"11096259","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 5 |
| Details | Region: {"description":"CDR2","evidences":[{"source":"PubMed","id":"11096259","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 14 |
| Details | Region: {"description":"T cell receptor beta joining 2-7","evidences":[{"source":"PubMed","id":"1833769","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 14 |
| Details | Region: {"description":"Connecting peptide","evidences":[{"source":"UniProtKB","id":"P01850","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27036003","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
