Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7FF9

Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0001217	molecular_function	DNA-binding transcription repressor activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0030552	molecular_function	cAMP binding
A	0032993	cellular_component	protein-DNA complex
A	0043565	molecular_function	sequence-specific DNA binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0001217	molecular_function	DNA-binding transcription repressor activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0030552	molecular_function	cAMP binding
B	0032993	cellular_component	protein-DNA complex
B	0043565	molecular_function	sequence-specific DNA binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0001216	molecular_function	DNA-binding transcription activator activity
C	0001217	molecular_function	DNA-binding transcription repressor activity
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0030552	molecular_function	cAMP binding
C	0032993	cellular_component	protein-DNA complex
C	0043565	molecular_function	sequence-specific DNA binding
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0001216	molecular_function	DNA-binding transcription activator activity
D	0001217	molecular_function	DNA-binding transcription repressor activity
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005829	cellular_component	cytosol
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0030552	molecular_function	cAMP binding
D	0032993	cellular_component	protein-DNA complex
D	0043565	molecular_function	sequence-specific DNA binding
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription
E	0000976	molecular_function	transcription cis-regulatory region binding
E	0001216	molecular_function	DNA-binding transcription activator activity
E	0001217	molecular_function	DNA-binding transcription repressor activity
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0005829	cellular_component	cytosol
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0030552	molecular_function	cAMP binding
E	0032993	cellular_component	protein-DNA complex
E	0043565	molecular_function	sequence-specific DNA binding
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
F	0000976	molecular_function	transcription cis-regulatory region binding
F	0001216	molecular_function	DNA-binding transcription activator activity
F	0001217	molecular_function	DNA-binding transcription repressor activity
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0005829	cellular_component	cytosol
F	0006351	biological_process	DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
F	0030552	molecular_function	cAMP binding
F	0032993	cellular_component	protein-DNA complex
F	0043565	molecular_function	sequence-specific DNA binding
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0045893	biological_process	positive regulation of DNA-templated transcription
G	0000976	molecular_function	transcription cis-regulatory region binding
G	0001216	molecular_function	DNA-binding transcription activator activity
G	0001217	molecular_function	DNA-binding transcription repressor activity
G	0003677	molecular_function	DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0005829	cellular_component	cytosol
G	0006351	biological_process	DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
G	0030552	molecular_function	cAMP binding
G	0032993	cellular_component	protein-DNA complex
G	0043565	molecular_function	sequence-specific DNA binding
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0045893	biological_process	positive regulation of DNA-templated transcription
H	0000976	molecular_function	transcription cis-regulatory region binding
H	0001216	molecular_function	DNA-binding transcription activator activity
H	0001217	molecular_function	DNA-binding transcription repressor activity
H	0003677	molecular_function	DNA binding
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0005829	cellular_component	cytosol
H	0006351	biological_process	DNA-templated transcription
H	0006355	biological_process	regulation of DNA-templated transcription
H	0030552	molecular_function	cAMP binding
H	0032993	cellular_component	protein-DNA complex
H	0043565	molecular_function	sequence-specific DNA binding
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00042
Number of Residues	24
Details	HTH_CRP_1 Crp-type HTH domain signature. ITRqeIGrIVGcSreMv.GRvLksL

Chain	Residue	Details
A	ILE172-LEU195

site_id	PS00888
Number of Residues	17
Details	CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIyAGDrCEtLFFIikG

Chain	Residue	Details
A	ILE31-GLY47

site_id	PS00889
Number of Residues	22
Details	CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGElGLfekegseqe..RSAwVrA

Chain	Residue	Details
A	PHE72-ALA93

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	152
Details	DNA_BIND: H-T-H motif => ECO:0000255\|PROSITE-ProRule:PRU00387

Chain	Residue	Details
A	ARG174-LYS193
B	ARG174-LYS193
C	ARG174-LYS193
D	ARG174-LYS193
E	ARG174-LYS193
F	ARG174-LYS193
G	ARG174-LYS193
H	ARG174-LYS193

site_id	SWS_FT_FI2
Number of Residues	48
Details	BINDING: BINDING => ECO:0000269\|PubMed:21665969, ECO:0007744\|PDB:2OZ6

Chain	Residue	Details
A	GLY73
B	GLY73
B	ARG87
B	THR132
B	ARG179
B	ARG185
C	ARG59
C	GLY73
C	ARG87
C	THR132
C	ARG179
C	ARG185
D	ARG59
D	GLY73
D	ARG87
D	THR132
D	ARG179
D	ARG185
E	ARG59
E	GLY73
E	ARG87
E	THR132
E	ARG179
E	ARG185
F	ARG59
F	GLY73
F	ARG87
F	THR132
F	ARG179
F	ARG185
G	ARG59
G	GLY73
G	ARG87
G	THR132
G	ARG179
G	ARG185
H	ARG59
H	GLY73
H	ARG87
H	THR132
H	ARG179
H	ARG185
A	ARG59
A	ARG87
A	THR132
A	ARG179
A	ARG185
B	ARG59

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)