7FAB

CRYSTAL STRUCTURE OF HUMAN IMMUNOGLOBULIN FRAGMENT FAB NEW REFINED AT 2.0 ANGSTROMS RESOLUTION

Replaces:  3FABReplaces:  1FABReplaces:  2FAB

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0003823	molecular_function	antigen binding
H	0005576	cellular_component	extracellular region
H	0005886	cellular_component	plasma membrane
H	0006955	biological_process	immune response
H	0016064	biological_process	immunoglobulin mediated immune response
L	0003823	molecular_function	antigen binding
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0016064	biological_process	immunoglobulin mediated immune response
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR187-HIS193
H	TYR198-HIS204

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	94
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"Complementarity-determining-1","evidences":[{"source":"UniProtKB","id":"P23083","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"Framework-2","evidences":[{"source":"UniProtKB","id":"P23083","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Region: {"description":"Complementarity-determining-2","evidences":[{"source":"UniProtKB","id":"P23083","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	37
Details	Region: {"description":"Framework-3","evidences":[{"source":"UniProtKB","id":"P23083","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Region: {"description":"Complementarity-determining-3","evidences":[{"source":"UniProtKB","id":"P23083","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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