7F6L
Crystal structure of human MUS81-EME2 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0006308 | biological_process | DNA catabolic process |
| A | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| B | 0000712 | biological_process | resolution of meiotic recombination intermediates |
| B | 0000723 | biological_process | telomere maintenance |
| B | 0000781 | cellular_component | chromosome, telomeric region |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004520 | molecular_function | DNA endonuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006281 | biological_process | DNA repair |
| B | 0006302 | biological_process | double-strand break repair |
| B | 0006310 | biological_process | DNA recombination |
| B | 0006974 | biological_process | DNA damage response |
| B | 0031297 | biological_process | replication fork processing |
| B | 0031573 | biological_process | mitotic intra-S DNA damage checkpoint signaling |
| B | 0043596 | cellular_component | nuclear replication fork |
| B | 0048476 | cellular_component | Holliday junction resolvase complex |
| B | 0071140 | biological_process | resolution of mitotic recombination intermediates |
| B | 0140767 | molecular_function | enzyme-substrate adaptor activity |
| B | 1905347 | cellular_component | endodeoxyribonuclease complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35290797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39015284","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4P0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9F99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9F9K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24733841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39015284","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4P0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9F9K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39015284","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9F9K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
