7EO5
Crystal structure of pyrano 1,3, oxazine derivative in complex with the second bromodomain of BRD2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue PGE A 601 |
| Chain | Residue |
| A | PRO347 |
| A | LYS351 |
| A | GLU404 |
| A | HOH735 |
| A | HOH763 |
| A | HOH775 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue BUX A 602 |
| Chain | Residue |
| A | LEU381 |
| A | LEU383 |
| A | CYS425 |
| A | TYR428 |
| A | ASN429 |
| A | HOH701 |
| A | HOH825 |
| A | PRO371 |
| A | PHE372 |
| A | VAL376 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
