Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0000166 | molecular_function | nucleotide binding |
| a | 0004540 | molecular_function | RNA nuclease activity |
| a | 0004672 | molecular_function | protein kinase activity |
| a | 0005524 | molecular_function | ATP binding |
| a | 0006397 | biological_process | mRNA processing |
| a | 0006468 | biological_process | protein phosphorylation |
| a | 0046872 | molecular_function | metal ion binding |
| b | 0000166 | molecular_function | nucleotide binding |
| b | 0004540 | molecular_function | RNA nuclease activity |
| b | 0004672 | molecular_function | protein kinase activity |
| b | 0005524 | molecular_function | ATP binding |
| b | 0006397 | biological_process | mRNA processing |
| b | 0006468 | biological_process | protein phosphorylation |
| b | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 25L a 801 |
| Chain | Residue |
| a | TRP56 |
| a | TYR133 |
| a | ARG153 |
| b | ARG307 |
| b | ARG308 |
| b | TYR310 |
| b | ARG353 |
| b | PHE362 |
| a | TRP58 |
| a | SER63 |
| a | GLN66 |
| a | LYS87 |
| a | ASN89 |
| a | ASP120 |
| a | PHE124 |
| a | GLU129 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue MYC a 802 |
| Chain | Residue |
| a | ARG340 |
| a | ILE369 |
| a | ALA370 |
| a | ILE377 |
| a | ALA388 |
| a | LEU432 |
| a | ALA433 |
| a | CYS435 |
| a | THR438 |
| a | GLU441 |
| a | LEU489 |
| a | ASP500 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 a 803 |
| Chain | Residue |
| a | ARG675 |
| a | HIS680 |
| b | ARG675 |
| b | HIS680 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue 25L b 801 |
| Chain | Residue |
| a | ARG307 |
| a | TYR310 |
| a | ARG353 |
| a | PHE362 |
| b | TRP56 |
| b | TRP58 |
| b | SER63 |
| b | GLN66 |
| b | LYS87 |
| b | ASN89 |
| b | ASP120 |
| b | ASN122 |
| b | PHE124 |
| b | GLU129 |
| b | TYR133 |
| b | ARG153 |
| b | GLY165 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue MYC b 802 |
| Chain | Residue |
| b | ARG340 |
| b | ILE369 |
| b | ALA370 |
| b | ALA388 |
| b | VAL416 |
| b | LEU432 |
| b | ALA433 |
| b | CYS435 |
| b | THR438 |
| b | GLU441 |
| b | LEU489 |
| b | ALA499 |
| b | ASP500 |
Functional Information from PROSITE/UniProt
| site_id | PS00066 |
| Number of Residues | 15 |
| Details | HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. KaEVdARDnMGrNaL |
| Chain | Residue | Details |
| a | LYS190-LEU204 | |
