7EBE

Crystal structure of Isocitrate lyase-1 from Candida albicans

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004451	molecular_function	isocitrate lyase activity
A	0005737	cellular_component	cytoplasm
A	0006097	biological_process	glyoxylate cycle
A	0006099	biological_process	tricarboxylic acid cycle
A	0009514	cellular_component	glyoxysome
A	0016829	molecular_function	lyase activity
A	0016833	molecular_function	oxo-acid-lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0046421	molecular_function	methylisocitrate lyase activity
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004451	molecular_function	isocitrate lyase activity
B	0005737	cellular_component	cytoplasm
B	0006097	biological_process	glyoxylate cycle
B	0006099	biological_process	tricarboxylic acid cycle
B	0009514	cellular_component	glyoxysome
B	0016829	molecular_function	lyase activity
B	0016833	molecular_function	oxo-acid-lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0046421	molecular_function	methylisocitrate lyase activity
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004451	molecular_function	isocitrate lyase activity
C	0005737	cellular_component	cytoplasm
C	0006097	biological_process	glyoxylate cycle
C	0006099	biological_process	tricarboxylic acid cycle
C	0009514	cellular_component	glyoxysome
C	0016829	molecular_function	lyase activity
C	0016833	molecular_function	oxo-acid-lyase activity
C	0019752	biological_process	carboxylic acid metabolic process
C	0046421	molecular_function	methylisocitrate lyase activity
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004451	molecular_function	isocitrate lyase activity
D	0005737	cellular_component	cytoplasm
D	0006097	biological_process	glyoxylate cycle
D	0006099	biological_process	tricarboxylic acid cycle
D	0009514	cellular_component	glyoxysome
D	0016829	molecular_function	lyase activity
D	0016833	molecular_function	oxo-acid-lyase activity
D	0019752	biological_process	carboxylic acid metabolic process
D	0046421	molecular_function	methylisocitrate lyase activity
D	0046872	molecular_function	metal ion binding
E	0003824	molecular_function	catalytic activity
E	0004451	molecular_function	isocitrate lyase activity
E	0005737	cellular_component	cytoplasm
E	0006097	biological_process	glyoxylate cycle
E	0006099	biological_process	tricarboxylic acid cycle
E	0009514	cellular_component	glyoxysome
E	0016829	molecular_function	lyase activity
E	0016833	molecular_function	oxo-acid-lyase activity
E	0019752	biological_process	carboxylic acid metabolic process
E	0046421	molecular_function	methylisocitrate lyase activity
E	0046872	molecular_function	metal ion binding
F	0003824	molecular_function	catalytic activity
F	0004451	molecular_function	isocitrate lyase activity
F	0005737	cellular_component	cytoplasm
F	0006097	biological_process	glyoxylate cycle
F	0006099	biological_process	tricarboxylic acid cycle
F	0009514	cellular_component	glyoxysome
F	0016829	molecular_function	lyase activity
F	0016833	molecular_function	oxo-acid-lyase activity
F	0019752	biological_process	carboxylic acid metabolic process
F	0046421	molecular_function	methylisocitrate lyase activity
F	0046872	molecular_function	metal ion binding
G	0003824	molecular_function	catalytic activity
G	0004451	molecular_function	isocitrate lyase activity
G	0005737	cellular_component	cytoplasm
G	0006097	biological_process	glyoxylate cycle
G	0006099	biological_process	tricarboxylic acid cycle
G	0009514	cellular_component	glyoxysome
G	0016829	molecular_function	lyase activity
G	0016833	molecular_function	oxo-acid-lyase activity
G	0019752	biological_process	carboxylic acid metabolic process
G	0046421	molecular_function	methylisocitrate lyase activity
G	0046872	molecular_function	metal ion binding
H	0003824	molecular_function	catalytic activity
H	0004451	molecular_function	isocitrate lyase activity
H	0005737	cellular_component	cytoplasm
H	0006097	biological_process	glyoxylate cycle
H	0006099	biological_process	tricarboxylic acid cycle
H	0009514	cellular_component	glyoxysome
H	0016829	molecular_function	lyase activity
H	0016833	molecular_function	oxo-acid-lyase activity
H	0019752	biological_process	carboxylic acid metabolic process
H	0046421	molecular_function	methylisocitrate lyase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00161
Number of Residues	6
Details	ISOCITRATE_LYASE Isocitrate lyase signature. KKCGHM

Chain	Residue	Details
A	LYS208-MET213

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P9WKK7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	80
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WKK7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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