Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7EBC

Crystal structure of Isocitrate lyase-1 from Saccaromyces cervisiae

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004451molecular_functionisocitrate lyase activity
A0005576cellular_componentextracellular region
A0005737cellular_componentcytoplasm
A0005773cellular_componentvacuole
A0006097biological_processglyoxylate cycle
A0006099biological_processtricarboxylic acid cycle
A0016829molecular_functionlyase activity
A0019752biological_processcarboxylic acid metabolic process
A0032787biological_processmonocarboxylic acid metabolic process
A0046421molecular_functionmethylisocitrate lyase activity
A0046872molecular_functionmetal ion binding
B0003824molecular_functioncatalytic activity
B0004451molecular_functionisocitrate lyase activity
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005773cellular_componentvacuole
B0006097biological_processglyoxylate cycle
B0006099biological_processtricarboxylic acid cycle
B0016829molecular_functionlyase activity
B0019752biological_processcarboxylic acid metabolic process
B0032787biological_processmonocarboxylic acid metabolic process
B0046421molecular_functionmethylisocitrate lyase activity
B0046872molecular_functionmetal ion binding
C0003824molecular_functioncatalytic activity
C0004451molecular_functionisocitrate lyase activity
C0005576cellular_componentextracellular region
C0005737cellular_componentcytoplasm
C0005773cellular_componentvacuole
C0006097biological_processglyoxylate cycle
C0006099biological_processtricarboxylic acid cycle
C0016829molecular_functionlyase activity
C0019752biological_processcarboxylic acid metabolic process
C0032787biological_processmonocarboxylic acid metabolic process
C0046421molecular_functionmethylisocitrate lyase activity
C0046872molecular_functionmetal ion binding
D0003824molecular_functioncatalytic activity
D0004451molecular_functionisocitrate lyase activity
D0005576cellular_componentextracellular region
D0005737cellular_componentcytoplasm
D0005773cellular_componentvacuole
D0006097biological_processglyoxylate cycle
D0006099biological_processtricarboxylic acid cycle
D0016829molecular_functionlyase activity
D0019752biological_processcarboxylic acid metabolic process
D0032787biological_processmonocarboxylic acid metabolic process
D0046421molecular_functionmethylisocitrate lyase activity
D0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00161
Number of Residues6
DetailsISOCITRATE_LYASE Isocitrate lyase signature. KKCGHM
ChainResidueDetails
ALYS215-MET220

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Proton acceptor => ECO:0000305
ChainResidueDetails
ACYS217
BCYS217
CCYS217
DCYS217

site_idSWS_FT_FI2
Number of Residues24
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P9WKK7
ChainResidueDetails
ASER106
BARG254
BASN437
BTHR471
CSER106
CASP179
CGLY218
CARG254
CASN437
CTHR471
DSER106
AASP179
DASP179
DGLY218
DARG254
DASN437
DTHR471
AGLY218
AARG254
AASN437
ATHR471
BSER106
BASP179
BGLY218

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0000255
ChainResidueDetails
ATHR53
BTHR53
CTHR53
DTHR53

224004

PDB entries from 2024-08-21

PDB statisticsPDBj update infoContact PDBjnumon