7E9M
Crystal Structure of Spindlin1 bound to SPINDOC Docpep3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005819 | cellular_component | spindle |
| A | 0005829 | cellular_component | cytosol |
| A | 0006325 | biological_process | chromatin organization |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0007276 | biological_process | gamete generation |
| A | 0009303 | biological_process | rRNA transcription |
| A | 0016055 | biological_process | Wnt signaling pathway |
| A | 0030177 | biological_process | positive regulation of Wnt signaling pathway |
| A | 0031965 | cellular_component | nuclear membrane |
| A | 0035064 | molecular_function | methylated histone binding |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| A | 0051321 | biological_process | meiotic cell cycle |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0005730 | cellular_component | nucleolus |
| C | 0005819 | cellular_component | spindle |
| C | 0005829 | cellular_component | cytosol |
| C | 0006325 | biological_process | chromatin organization |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0007276 | biological_process | gamete generation |
| C | 0009303 | biological_process | rRNA transcription |
| C | 0016055 | biological_process | Wnt signaling pathway |
| C | 0030177 | biological_process | positive regulation of Wnt signaling pathway |
| C | 0031965 | cellular_component | nuclear membrane |
| C | 0035064 | molecular_function | methylated histone binding |
| C | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| C | 0051321 | biological_process | meiotic cell cycle |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | SITE: Histone H3K4me3 and H3R8me2a binding |
| Chain | Residue | Details |
| A | ASP173 | |
| A | GLN180 | |
| A | ASP184 | |
| C | ASP173 | |
| C | GLN180 | |
| C | ASP184 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q61142 |
| Chain | Residue | Details |
| A | LYS44 | |
| C | LYS44 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by AURKA => ECO:0000269|PubMed:22258766 |
| Chain | Residue | Details |
| A | SER109 | |
| C | SER109 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by AURKA => ECO:0000269|PubMed:22258766, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER124 | |
| C | SER124 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER199 | |
| C | SER199 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS7 | |
| A | LYS28 | |
| C | LYS7 | |
| C | LYS28 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS44 | |
| C | LYS44 |
