7E9M

Crystal Structure of Spindlin1 bound to SPINDOC Docpep3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of DNA-templated transcription
A	0007276	biological_process	gamete generation
A	0009303	biological_process	rRNA transcription
A	0016055	biological_process	Wnt signaling pathway
A	0030177	biological_process	positive regulation of Wnt signaling pathway
A	0031965	cellular_component	nuclear membrane
A	0035064	molecular_function	obsolete methylated histone binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0051321	biological_process	meiotic cell cycle
A	0071168	biological_process	protein localization to chromatin
A	0140002	molecular_function	histone H3K4me3 reader activity
A	0140566	molecular_function	histone reader activity
A	0141196	biological_process	transposable element silencing by piRNA-mediated DNA methylation
C	0000785	cellular_component	chromatin
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005819	cellular_component	spindle
C	0005829	cellular_component	cytosol
C	0006325	biological_process	chromatin organization
C	0006355	biological_process	regulation of DNA-templated transcription
C	0007276	biological_process	gamete generation
C	0009303	biological_process	rRNA transcription
C	0016055	biological_process	Wnt signaling pathway
C	0030177	biological_process	positive regulation of Wnt signaling pathway
C	0031965	cellular_component	nuclear membrane
C	0035064	molecular_function	obsolete methylated histone binding
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0051321	biological_process	meiotic cell cycle
C	0071168	biological_process	protein localization to chromatin
C	0140002	molecular_function	histone H3K4me3 reader activity
C	0140566	molecular_function	histone reader activity
C	0141196	biological_process	transposable element silencing by piRNA-mediated DNA methylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	126
Details	Region: {"description":"Tudor-like domain 1","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Region: {"description":"Histone H3K4me3 and H3R8me2a binding","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	122
Details	Region: {"description":"Tudor-like domain 2","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	98
Details	Region: {"description":"Tudor-like domain 3","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Site: {"description":"Histone H3K4me3 and H3R8me2a binding","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by AURKA","evidences":[{"source":"PubMed","id":"22258766","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---