7E9M
Crystal Structure of Spindlin1 bound to SPINDOC Docpep3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000785 | cellular_component | chromatin |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005819 | cellular_component | spindle |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0007276 | biological_process | gamete generation |
| A | 0009303 | biological_process | rRNA transcription |
| A | 0030177 | biological_process | positive regulation of Wnt signaling pathway |
| A | 0035064 | molecular_function | obsolete methylated histone binding |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| A | 0071168 | biological_process | protein localization to chromatin |
| A | 0140002 | molecular_function | histone H3K4me3 reader activity |
| A | 0140566 | molecular_function | histone reader activity |
| A | 0141196 | biological_process | transposable element silencing by piRNA-mediated DNA methylation |
| C | 0000785 | cellular_component | chromatin |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0005730 | cellular_component | nucleolus |
| C | 0005819 | cellular_component | spindle |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0007276 | biological_process | gamete generation |
| C | 0009303 | biological_process | rRNA transcription |
| C | 0030177 | biological_process | positive regulation of Wnt signaling pathway |
| C | 0035064 | molecular_function | obsolete methylated histone binding |
| C | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| C | 0071168 | biological_process | protein localization to chromatin |
| C | 0140002 | molecular_function | histone H3K4me3 reader activity |
| C | 0140566 | molecular_function | histone reader activity |
| C | 0141196 | biological_process | transposable element silencing by piRNA-mediated DNA methylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 126 |
| Details | Region: {"description":"Tudor-like domain 1","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"Histone H3K4me3 and H3R8me2a binding","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 122 |
| Details | Region: {"description":"Tudor-like domain 2","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 98 |
| Details | Region: {"description":"Tudor-like domain 3","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Site: {"description":"Histone H3K4me3 and H3R8me2a binding","evidences":[{"source":"PubMed","id":"23077255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24589551","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by AURKA","evidences":[{"source":"PubMed","id":"22258766","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
