7E7Z
CryoEM structure of the human Kv4.2-KChIP1 complex, transmembrane region
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005249 | molecular_function | voltage-gated potassium channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0008076 | cellular_component | voltage-gated potassium channel complex |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005249 | molecular_function | voltage-gated potassium channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0008076 | cellular_component | voltage-gated potassium channel complex |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005249 | molecular_function | voltage-gated potassium channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0008076 | cellular_component | voltage-gated potassium channel complex |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005249 | molecular_function | voltage-gated potassium channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0008076 | cellular_component | voltage-gated potassium channel complex |
| D | 0016020 | cellular_component | membrane |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=Segment S1 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| B | MET183-VAL204 | |
| A | MET183-VAL204 | |
| C | MET183-VAL204 | |
| D | MET183-VAL204 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 192 |
| Details | TOPO_DOM: Extracellular => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | GLU205-ALA228 | |
| A | THR280-SER286 | |
| A | TYR344-ILE357 | |
| A | PRO378-LYS384 | |
| B | GLU205-ALA228 | |
| B | THR280-SER286 | |
| B | TYR344-ILE357 | |
| B | PRO378-LYS384 | |
| C | GLU205-ALA228 | |
| C | THR280-SER286 | |
| C | TYR344-ILE357 | |
| C | PRO378-LYS384 | |
| D | GLU205-ALA228 | |
| D | THR280-SER286 | |
| D | TYR344-ILE357 | |
| D | PRO378-LYS384 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=Segment S2 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | PHE229-ALA250 | |
| B | PHE229-ALA250 | |
| C | PHE229-ALA250 | |
| D | PHE229-ALA250 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 96 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | ALA251-VAL261 | |
| A | SER307-ALA321 | |
| B | ALA251-VAL261 | |
| B | SER307-ALA321 | |
| C | ALA251-VAL261 | |
| C | SER307-ALA321 | |
| D | ALA251-VAL261 | |
| D | SER307-ALA321 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 68 |
| Details | TRANSMEM: Helical; Name=Segment S3 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | MET262-MET279 | |
| B | MET262-MET279 | |
| C | MET262-MET279 | |
| D | MET262-MET279 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 76 |
| Details | TRANSMEM: Helical; Voltage-sensor; Name=Segment S4 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | GLY287-HIS306 | |
| B | GLY287-HIS306 | |
| C | GLY287-HIS306 | |
| D | GLY287-HIS306 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=Segment S5 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | SER322-PHE343 | |
| B | SER322-PHE343 | |
| C | SER322-PHE343 | |
| D | SER322-PHE343 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 44 |
| Details | INTRAMEM: Helical; Name=Pore helix => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | PRO358-THR369 | |
| B | PRO358-THR369 | |
| C | PRO358-THR369 | |
| D | PRO358-THR369 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 28 |
| Details | INTRAMEM: INTRAMEM => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | THR370-VAL377 | |
| B | THR370-VAL377 | |
| C | THR370-VAL377 | |
| D | THR370-VAL377 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 112 |
| Details | TRANSMEM: Helical; Name=Segment S6 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | ILE385-TYR413 | |
| B | ILE385-TYR413 | |
| C | ILE385-TYR413 | |
| D | ILE385-TYR413 |
