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7E58

interferon-inducible anti-viral protein 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0002218biological_processactivation of innate immune response
A0003924molecular_functionGTPase activity
A0004866molecular_functionendopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0006955biological_processimmune response
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0030659cellular_componentcytoplasmic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0034504biological_processprotein localization to nucleus
A0042742biological_processdefense response to bacterium
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0042832biological_processdefense response to protozoan
A0045087biological_processinnate immune response
A0048471cellular_componentperinuclear region of cytoplasm
A0050830biological_processdefense response to Gram-positive bacterium
A0051607biological_processdefense response to virus
A0051715biological_processcytolysis in another organism
A0071222biological_processcellular response to lipopolysaccharide
A0071346biological_processcellular response to type II interferon
A0071347biological_processcellular response to interleukin-1
A0071356biological_processcellular response to tumor necrosis factor
A0140639biological_processpositive regulation of pyroptotic inflammatory response
A0140678molecular_functionmolecular function inhibitor activity
A0140973biological_processpositive regulation of AIM2 inflammasome complex assembly
B0000139cellular_componentGolgi membrane
B0002218biological_processactivation of innate immune response
B0003924molecular_functionGTPase activity
B0004866molecular_functionendopeptidase inhibitor activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0006955biological_processimmune response
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0030659cellular_componentcytoplasmic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0034504biological_processprotein localization to nucleus
B0042742biological_processdefense response to bacterium
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0042832biological_processdefense response to protozoan
B0045087biological_processinnate immune response
B0048471cellular_componentperinuclear region of cytoplasm
B0050830biological_processdefense response to Gram-positive bacterium
B0051607biological_processdefense response to virus
B0051715biological_processcytolysis in another organism
B0071222biological_processcellular response to lipopolysaccharide
B0071346biological_processcellular response to type II interferon
B0071347biological_processcellular response to interleukin-1
B0071356biological_processcellular response to tumor necrosis factor
B0140639biological_processpositive regulation of pyroptotic inflammatory response
B0140678molecular_functionmolecular function inhibitor activity
B0140973biological_processpositive regulation of AIM2 inflammasome complex assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q96PP8
ChainResidueDetails
AGLY45
AARG181
ALEU245
BGLY45
BARG181
BLEU245

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Cysteine methyl ester => ECO:0000305|PubMed:21151871
ChainResidueDetails
ACYS588
BCYS588

site_idSWS_FT_FI3
Number of Residues2
DetailsLIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:21151871, ECO:0000305|PubMed:31091448
ChainResidueDetails
ACYS588
BCYS588

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PDB entries from 2024-07-17

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