7E55
Cryo-EM structure of alpha 7 homo-tetradecamer
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000502 | cellular_component | proteasome complex |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005839 | cellular_component | proteasome core complex |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| A | 0010498 | biological_process | proteasomal protein catabolic process |
| A | 0019773 | cellular_component | proteasome core complex, alpha-subunit complex |
| A | 0031625 | molecular_function | ubiquitin protein ligase binding |
| A | 0043161 | biological_process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| A | 0045202 | cellular_component | synapse |
| A | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| A | 0052548 | biological_process | regulation of endopeptidase activity |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PROSITE/UniProt
| site_id | PS00388 |
| Number of Residues | 23 |
| Details | PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdlsaStFSPdGRvfQVEYAmkA |
| Chain | Residue | Details |
| A | TYR7-ALA29 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0000269|PubMed:12376572, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | SER1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS56 | |
| A | LYS205 | |
| A | LYS229 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17323924, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER242 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:12376572, ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:17323924, ECO:0007744|PubMed:17487921, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19367720, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER249 |
