7E2E
Crystal structure of the Estrogen-Related Receptor alpha (ERRalpha) ligand-binding domain (LBD) in complex with an agonist DS45500853 and a PGC-1alpha peptide
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | binding site for residue HVO A 601 |
Chain | Residue |
A | PHE328 |
A | VAL369 |
A | PHE382 |
A | LEU405 |
A | PHE495 |
A | VAL504 |
A | HOH701 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue IOD P 301 |
Chain | Residue |
P | ALA207 |
Q | ALA207 |
A | MET354 |
B | MET354 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue HVO B 601 |
Chain | Residue |
B | PHE328 |
B | VAL369 |
B | PHE382 |
B | LEU405 |
B | PHE495 |
B | HOH701 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
A | LYS499 | |
B | LYS499 |